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AI system can create novel proteins using generative diffusion

Researchers at the University of Toronto have developed an artificial intelligence system that can create proteins not found in nature using generative diffusion, the same technology behind popular image-creation platforms such as DALL-E and Midjourney.

5 May 2023

Study analyzes effects of a calorie-restricted diet on the hippocampus in old rats

A study coordinated by the Institute of Neurosciences of the UAB (INc-UAB) analyzes in old rats the effects of a calorie-restricted diet on the hippocampus, a brain structure that is critical in learning and memory processes.

5 May 2023

Unlocking the puzzle: How ACE2 shapes macrophage responses in COVID-19

A new study investigates whether SARS-CoV-2 can enter and replicate in macrophages and whether ACE2 is involved in these mechanisms.

4 May 2023

Membrane lipid remodeling alters key enzyme involved in Alzheimer’s

Adding long-chain fatty acids can thicken cell membranes and alter the activity of a key enzyme, as LMU scientists have demonstrated in cell cultures.

4 May 2023

Powerful two-photon microscopy for imaging fast biological processes

Two-photon microscopy (TPM) has revolutionized the field of biology by enabling researchers to observe complex biological processes in living tissues at high resolution.

4 May 2023

Revving up COVID mRNA vaccines: Algorithm generates 128-fold increase in antibodies

Research paper proposes a new method for predicting highly expressed genes based on codon usage bias and minimum free energy of mRNA secondary structures. The method involves constructing a stochastic grammar that generates sequences with high CAI and low MFE, and testing it on two mRNA vaccines.

3 May 2023

Organoid models provide new scientific insights into a rare childhood liver cancer

Scientists of the Princess Máxima Center for pediatric oncology and Hubrecht Institute in the Netherlands have revealed new scientific insights into the features of fibrolamellar carcinoma (FLC), a rare type of childhood liver cancer

3 May 2023

Researchers measure the effect of all possible variants of GCK gene

Researchers at the Department of Biology, University of Copenhagen, have now contributed to solving this problem for a specific gene called GCK. The study has just been published in Genome Biology.

3 May 2023

Diet has a much stronger impact on intestinal microbiota than defensins

Researchers at Umeå University, Sweden, have found that among the many factors that shape the intestinal microbiota composition, diet has a much stronger impact than defensins, which are intestinal defence molecules produced by the body.

3 May 2023

Finnish mitochondrial disease of newborns shows cancer-like changes in proliferating cells

A study found that a mitochondrial disease of newborns shows cancer-like changes in proliferating cells, causing tissues to age prematurely.

3 May 2023

Using PandaOmics to identify dual-purpose therapeutic targets to treat aging and glioblastoma

A new research paper was published in Aging (listed by MEDLINE/PubMed as "Aging (Albany NY)" and "Aging-US" by Web of Science) Volume 15, Issue 8, entitled, "Identification of dual-purpose therapeutic targets implicated in aging and glioblastoma multiforme using PandaOmics - an AI-enabled biological target discovery platform."

3 May 2023

New framework offers roadmap for developing sustainable dietary guidelines

Research paper presents a framework for developing sustainable food-based dietary guidelines that consider both nutritional requirements and environmental sustainability. The framework consists of five steps that can be adapted to any country.

2 May 2023

Researchers develop a deep learning model to classify cancer cells by type

Cancer cells that initiate metastasis, or the spread of the disease from its primary location, are different from cancer cells that stay in the original tumor. Distinguishing metastasis-initiating cell types can determine the severity of cancer and help medical practitioners decide on a course of treatment.

2 May 2023

African psychedelic plant medicine inspires new drug candidates for treating addiction and depression

Scientists have developed two new drug candidates for potentially treating addiction and depression, modeled on the pharmacology of a traditional African psychedelic plant medicine called ibogaine.

2 May 2023

Genome-based surveillance offers new hope in the fight against healthcare-associated infections

Researchers discuss major healthcare-associated pathogens, as well as current and future public health priorities related to these microorganisms.

2 May 2023

Novel chronic murine wound mouse model to study cellular senescence

A new research paper was published on the cover of Aging (listed by MEDLINE/PubMed as "Aging (Albany NY)" and "Aging-US" by Web of Science) Volume 15, Issue 8, entitled, "A chronic wound model to investigate skin cellular senescence."

2 May 2023

New insight into how the occludin protein mediates cell-to-cell transmission of SARS-CoV-2 virus

While the coronavirus continues to infect people around the world, researchers at the University of Missouri have identified a specific protein inside the human body that plays a critical role in how the virus spreads from cell to cell after infection -; a discovery that will help better understand the COVID-19 disease and could lead to the development of new antiviral drugs in the future.

2 May 2023

Life Science News

AI system can create novel proteins using generative diffusion

Study analyzes effects of a calorie-restricted diet on the hippocampus in old rats

Unlocking the puzzle: How ACE2 shapes macrophage responses in COVID-19

Membrane lipid remodeling alters key enzyme involved in Alzheimer’s

Powerful two-photon microscopy for imaging fast biological processes

Revving up COVID mRNA vaccines: Algorithm generates 128-fold increase in antibodies

Organoid models provide new scientific insights into a rare childhood liver cancer

Researchers measure the effect of all possible variants of GCK gene

Diet has a much stronger impact on intestinal microbiota than defensins

Finnish mitochondrial disease of newborns shows cancer-like changes in proliferating cells

Using PandaOmics to identify dual-purpose therapeutic targets to treat aging and glioblastoma

New framework offers roadmap for developing sustainable dietary guidelines

Researchers develop a deep learning model to classify cancer cells by type

African psychedelic plant medicine inspires new drug candidates for treating addiction and depression

Genome-based surveillance offers new hope in the fight against healthcare-associated infections

Novel chronic murine wound mouse model to study cellular senescence

New insight into how the occludin protein mediates cell-to-cell transmission of SARS-CoV-2 virus

Paving the Way for New Drugs through Particle Perfection

Virologist investigates Huanan seafood market's SARS-CoV-2 origins: Unexpected genetic connections revealed

Structure of protein methyltransferase from the monkeypox virus deciphered

Small solutions for big problems in drug discovery and delivery

Professor Nancy Ip: Pioneering New Paths in Neurodegenerative Therapy

Utilizing process Raman in optimizing cultivated meat production

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