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CRISPR-Cas9 system can help reduce adenovirus replication in human cells

The replication of potentially harmful adenoviruses can be significantly reduced in human cells in cell culture by using the so-called CRISPR-Cas9 system ("gene scissors")

29 Apr 2023

A dimensional reduction strategy for enhanced cryopreservation of red blood cells

Small amounts of nanometer-thin metal-organic layers efficiently protect red blood cells during freezing and thawing, as a team of researchers writing in the journal Angewandte Chemie has discovered. The nanolayers, made from metal-organic frameworks based on the metal hafnium, prevent ice crystal formation at very low concentrations. This effective novel cryoprotection mode could be used to develop new and more efficient cryoprotectants for the biosciences.

29 Apr 2023

Imbalanced electrical charges in biomolecular condensates spark redox reactions

The human body relies heavily on electrical charges. Lightning-like pulses of energy fly through the brain and nerves and most biological processes depend on electrical ions traveling across the membranes of each cell in our body.

28 Apr 2023

New approach for efficient engineering of cell and gene therapies

A new approach to the genetic engineering of cells promises significant improvements in speed, efficiency, and reduction in cellular toxicity compared to current methods.

28 Apr 2023

Scientists identify broad-spectrum antiviral agents that can target multiple RNA virus families

A new study has identified potential broad-spectrum antiviral agents that can target multiple families of RNA viruses that continue to pose a significant threat for future pandemics.

28 Apr 2023

Cryogenic electron microscopy helps visualize structural details of gene regulation process

LMU researchers show detailed displacement process of TBP transcription factor from DNA by Mot1 enzyme.

28 Apr 2023

Researchers develop novel bio-inspired molecules to enhance bone regeneration

People's ability to regenerate bones declines with age and is further decreased by diseases such as osteoporosis.

28 Apr 2023

Study uncovers a universal molecular-level explanation for biological homeostasis and adaptation

Landmark research published in Nature Communications by mathematicians Dr Robyn Araujo at QUT and Professor Lance Liotta of George Mason University in the US sets out the definitive picture of biological adaptation at the level of intermolecular interactions.

28 Apr 2023

Revolutionizing drug discovery: Giga-scale screening unleashes power of AI and virtual libraries

Research discusses recent advances in computer-aided drug discovery, including the use of virtual screening and deep learning methods and their potential to revolutionize the drug discovery process by identifying diverse, potent, and drug-like ligands to protein targets.

28 Apr 2023

Study findings could be harnessed to engineer new botulinum neurotoxin E variants

A team of researchers from the University of California, Irvine, have revealed the first crystal structures of the receptor-binding domain of botulinum neurotoxin E (BoNT/E) in complex with its human neuronal receptors, synaptic vesicle glycoprotein 2A (SV2A).

27 Apr 2023

New strategy for identifying small molecules offers a promising path for discovering targeted drugs

Scripps Research scientists have developed a new strategy for identifying small molecules that can change the function of proteins, offering a promising path for discovering targeted drugs.

27 Apr 2023

Insomnia drug shows potential as an effective treatment for opioid use disorder

The insomnia drug suvorexant (Belsomra) might be an effective treatment for opioid use disorder, according to a preclinical study from Scripps Research.

27 Apr 2023

Study uncovers new clues and raises more questions about CRISPR

CRISPR claimed scientific fame for its ability to quickly and accurately edit genes. But, at the core, CRISPR systems are immune systems that help bacteria protect themselves from viruses by targeting and destroying viral DNA and RNA.

27 Apr 2023

"Deleted" pieces of genetic information may be crucial to the development of humankind

What the human genome is lacking compared with the genomes of other primates might have been as crucial to the development of humankind as what has been added during our evolutionary history, according to a new study led by researchers at Yale and the Broad Institute of MIT and Harvard.

27 Apr 2023

3D genome mapping may lead to the treatment of deadliest pediatric brain tumors

Researchers led by Sanford Burnham Prebys assistant professor Lukas Chavez, Ph.D., are leveraging the latest technology to take a never-before-seen look at ependymoma, one of the deadliest pediatric brain tumors.

27 Apr 2023

UC research examines link between genetics and the presence of opioid use disorder

New research out of the University of Cincinnati examines the association between genetics and the presence of opioid use disorder.

27 Apr 2023

How inert, sleeping bacteria spring back to life

Solving a riddle that has confounded biologists since bacterial spores -; inert, sleeping bacteria -; were first described more than 150 years ago, researchers at Harvard Medical School have discovered a new kind of cellular sensor that allows spores to detect the presence of nutrients in their environment and quickly spring back to life.

27 Apr 2023

Life Science News

CRISPR-Cas9 system can help reduce adenovirus replication in human cells

A dimensional reduction strategy for enhanced cryopreservation of red blood cells

Imbalanced electrical charges in biomolecular condensates spark redox reactions

New approach for efficient engineering of cell and gene therapies

Scientists identify broad-spectrum antiviral agents that can target multiple RNA virus families

Cryogenic electron microscopy helps visualize structural details of gene regulation process

Researchers develop novel bio-inspired molecules to enhance bone regeneration

Study uncovers a universal molecular-level explanation for biological homeostasis and adaptation

Revolutionizing drug discovery: Giga-scale screening unleashes power of AI and virtual libraries

Study findings could be harnessed to engineer new botulinum neurotoxin E variants

New strategy for identifying small molecules offers a promising path for discovering targeted drugs

Insomnia drug shows potential as an effective treatment for opioid use disorder

Study uncovers new clues and raises more questions about CRISPR

"Deleted" pieces of genetic information may be crucial to the development of humankind

3D genome mapping may lead to the treatment of deadliest pediatric brain tumors

UC research examines link between genetics and the presence of opioid use disorder

How inert, sleeping bacteria spring back to life

Advanced DNA sequencing technique reveals the reason for COVID-19 related sudden child mortality

HORIBA introduces simple in-house PCR test for faster strangles diagnosis

Study reveals the mechanism behind oligomeric assembly of a BAR-domain-containing protein

Small solutions for big problems in drug discovery and delivery

Professor Nancy Ip: Pioneering New Paths in Neurodegenerative Therapy

Utilizing process Raman in optimizing cultivated meat production

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