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Study paves way for developing effective ASO therapies for brain diseases with fewer side effects

A promising therapy for a range of brain diseases involves antisense oligonucleotides (ASOs)-;specialized molecules that can modulate RNA and alter protein production-;directly injected into the cerebrospinal fluid, in the space around the brain and spinal cord.

14 Mar 2023

XBP1s plays a key role in controlling IL-15-mediated NK cell survival, study shows

A new study published in Science Immunology points to a promising therapeutic approach for future cancer treatments based on natural killer cells (NK), which are immune cells that bind to tumor cells and destroy them.

14 Mar 2023

Using antagonistic drug combinations for selective killing of resistant cancer cells

A new review paper was published in Oncotarget's Volume 14 on March 11, 2023, entitled, "Selective protection of normal cells from chemotherapy, while killing drug-resistant cancer cells."

14 Mar 2023

Host immune system forms small lesions in the intestines in response to bacterial infection

Yersinia bacteria cause a variety of human and animal diseases, the most notorious being the plague, caused by Yersinia pestis.

14 Mar 2023

Understanding how cells adjust in real time to withstand stresses on our health

Every minute of every day, our body adapts to meet the needs of each moment. When we binge on carbs, exercise, or become sick, chemical reactions inside our cells switch on, slow down, or shift strategy so that we have the energy and strength we need.

14 Mar 2023

Study shows SARS-CoV-2 causes DNA damage and elicits an altered DNA damage response

Researchers assessed the association between SARS-CoV-2 infection and DNA damage and cellular senescence.

14 Mar 2023

CN Bio appoints Deepak Singh as Vice President of Sales and Marketing

CN Bio has today announced that is has appointed Deepak Singh as Vice President of Sales and Marketing.

From CN-Bio 14 Mar 2023

Veterans’ health administration expands deployment of Mikroscan Systems

Mikroscan Technologies, innovators and manufacturers of live robotic microscopy and whole-slide imaging (WSI) systems, announces that it has expanded its relationship with the Veterans’ Administration through the multi-system sale of its SL5-20 Real-Time Telemicroscopy and Digital Pathology systems.

From Mikroscan Technologies 14 Mar 2023

Bispecific antibody shows improved efficacy against SARS-CoV-2 variants

Researchers from The University of Texas MD Anderson Cancer Center have developed fully human bispecific antibodies, as revealed in a recent study. These antibodies can bind to two distinct epitopes of the receptor binding domain (RBD) of the SARS-CoV-2 spike protein and have demonstrated the ability to neutralize various strains of the virus, including the Omicron variant.

14 Mar 2023

Hyperinflammation triggers long COVID headaches

Researchers characterize the immunological and metabolic alterations involved in chronic headache onset during post-acute sequelae of COVID-19.

13 Mar 2023

Study reveals the shared genetic basis for endometriosis and other pain conditions

University of Queensland researchers have contributed to the largest ever genetic study of endometriosis, finding new data about the variants that increase risk of the disease.

13 Mar 2023

Wayne State team discovers a simple technology to detect active TB infection antibodies

A team of faculty from Wayne State University has discovered new technology that will quickly and easily detect active Mycobacterium tuberculosis (TB) infection antibodies.

13 Mar 2023

Schizophrenia risk conferred by rare damaging genetic variants is conserved across ethnicities

Researchers have identified two previously unknown genes linked to schizophrenia and newly implicated a third gene as carrying risk for both schizophrenia and autism.

13 Mar 2023

TbID-based proteomic profiling in meiotic cells helps identify proximate proteins in A. thaliana

During meiosis, reshuffling of genetic information between homologous chromosomes through meiotic recombination creates variable gametes and hence genetic variation in offsprings.

13 Mar 2023

The right combination of bile salt hydrolases may offer a new approach to treat C. diff

Not all probiotics are created equal. In a new study, researchers found that certain enzymes within a class known as bile salt hydrolases (BSHs) can restrict Clostridioides difficile (C. diff.) colonization by both altering existing bile acids and by creating a new class of bile acids within the gut's microbial environment.

13 Mar 2023

Life Science News

Study paves way for developing effective ASO therapies for brain diseases with fewer side effects

XBP1s plays a key role in controlling IL-15-mediated NK cell survival, study shows

Using antagonistic drug combinations for selective killing of resistant cancer cells

Host immune system forms small lesions in the intestines in response to bacterial infection

Understanding how cells adjust in real time to withstand stresses on our health

Study shows SARS-CoV-2 causes DNA damage and elicits an altered DNA damage response

CN Bio appoints Deepak Singh as Vice President of Sales and Marketing

Veterans’ health administration expands deployment of Mikroscan Systems

Bispecific antibody shows improved efficacy against SARS-CoV-2 variants

Hyperinflammation triggers long COVID headaches

Study reveals the shared genetic basis for endometriosis and other pain conditions

Wayne State team discovers a simple technology to detect active TB infection antibodies

Schizophrenia risk conferred by rare damaging genetic variants is conserved across ethnicities

TbID-based proteomic profiling in meiotic cells helps identify proximate proteins in A. thaliana

The right combination of bile salt hydrolases may offer a new approach to treat C. diff

High-throughput genetic screening approach to study antibiotic proteins made by bacteriophages

Components of the gut microbiome could be used to better predict efficacy of CAR-T cell therapy

New study focuses on genetic diversity of E. coli bacteria in hospitalized patients

Using convolutional neural network to automate the identification of chromatid cohesion defects

New tool allows researchers to perform genetic screens of cell-cell interactions

Small solutions for big problems in drug discovery and delivery

Professor Nancy Ip: Pioneering New Paths in Neurodegenerative Therapy

Utilizing process Raman in optimizing cultivated meat production

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