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Remnants of ancient viruses in the human genome are active in normal tissues

Remnants of ancient viruses in the human genome are active in healthy tissues as well as diseased ones, limiting their utility as disease biomarkers, according to a study by Aidan Burn at Tufts University in Boston, USA and colleagues, publishing October 18th in the open access journal PLOS Biology.

18 Oct 2022

Unc5-GPC3 complex modulates the migration of neurons and brain-derived cancer cells

During brain development, neurons have to migrate long distances through complex environments until they reach their final destination.

18 Oct 2022

Study reveals how a cell signaling molecule can help oral cancer cells acquire high motility

The process of metastasis is when cancer cells gain motility and spread to other sites of the body. Because this is one of the main causes of cancer-related deaths, researchers have aimed to develop therapeutic strategies that can block metastasis.

18 Oct 2022

Study identifies genetic variation that influences lithium-induced neural proliferation

Bipolar disorder, a neuropsychiatric condition that includes manic and depressive episodes, affects about 1% of the population and is strongly influenced by genetics.

18 Oct 2022

Researchers identify gene associated with strong immune response after COVID-19 vaccination

Researchers from the University of Oxford have today reported new findings from a study exploring how certain genes can help generate a strong immune response following vaccination with two commonly used COVID-19 vaccines - identifying a particular gene associated with a high antibody response.

18 Oct 2022

New machine learning model can screen novel drug compounds to accurately predict efficacy in humans

The journey between identifying a potential therapeutic compound and Food and Drug Administration approval of a new drug can take well over a decade and cost upwards of a billion dollars.

18 Oct 2022

Recent innovations in infectious disease diagnostics

A recent Clinical Biochemistry editorial reports the latest innovations in the field of infectious disease diagnostics.

17 Oct 2022

Newly identified brain molecule orchestrates the immune system's responses to Alzheimer's and MS

UVA Health researchers have discovered a molecule in the brain responsible for orchestrating the immune system's responses to Alzheimer's disease and multiple sclerosis (MS), potentially allowing doctors to supercharge the body's ability to fight those and other devastating neurological diseases.

17 Oct 2022

Genetic signature predicts tumor metastases and patient survival in clear cell kidney cancer

Among patients with kidney cancer, the activity of four specific genes in the cancer cells seems to be able to predict the risk of the tumor spreading and the patient's chances of survival.

17 Oct 2022

KAUST study reveals unexpected role for zinc in the prevention of Parkinson's disease

Revealing zinc's interaction with a critical transport protein underscores the need to study biological pathways under physiologically relevant conditions.

17 Oct 2022

In silico studies identify potent plant metabolites capable of inhibiting SARS-CoV-2

In silico studies assess the binding efficacy of phytoconstituents against active sites of SARS-CoV-2.

16 Oct 2022

Researchers find a reproducible way to study cellular functions of plants cells with 3D bioprinting

A new study from North Carolina State University shows a reproducible way of studying cellular communication among varied types of plant cells by "bioprinting" these cells via a 3D printer.

14 Oct 2022

Fluctuating oxygen levels could have accelerated the development of early animal life

Oxygen levels in the Earth's atmosphere are likely to have "fluctuated wildly" one billion years ago, creating conditions that could have accelerated the development of early animal life, according to new research.

14 Oct 2022

Widespread variations in retroviral establishment and distribution among Darwin's finches

Vertebrate genomes are repositories for retrovirus code that was deposited into germ line as inherited endogenous retroviruses during evolution.

14 Oct 2022

Newly identified process keeps some immune cells on their toes

Cancer cells use an unusual mechanism to migrate into new tissue and form metastases there. The same process probably also keeps some immune cells on their toes.

14 Oct 2022

Pain-sensing neurons protect the gut from inflammation and associated tissue damage

Neurons that sense pain protect the gut from inflammation and associated tissue damage by regulating the microbial community living in the intestines, according to a study from researchers at Weill Cornell Medicine.

14 Oct 2022

Study determines how fibroblasts play a role in tumor's ability to generate anti-HER2 therapy resistance

A study led by researchers at the Hospital del Mar Medical Research Institute (IMIM-Hospital del Mar) has determined the role that fibroblasts, the cells that contribute to tissue formation, play in a tumor's ability to generate resistance to the most common biological treatment for HER2.

14 Oct 2022

Life Science News

Remnants of ancient viruses in the human genome are active in normal tissues

Unc5-GPC3 complex modulates the migration of neurons and brain-derived cancer cells

Study reveals how a cell signaling molecule can help oral cancer cells acquire high motility

Study identifies genetic variation that influences lithium-induced neural proliferation

Researchers identify gene associated with strong immune response after COVID-19 vaccination

New machine learning model can screen novel drug compounds to accurately predict efficacy in humans

Recent innovations in infectious disease diagnostics

Newly identified brain molecule orchestrates the immune system's responses to Alzheimer's and MS

Genetic signature predicts tumor metastases and patient survival in clear cell kidney cancer

KAUST study reveals unexpected role for zinc in the prevention of Parkinson's disease

In silico studies identify potent plant metabolites capable of inhibiting SARS-CoV-2

Researchers find a reproducible way to study cellular functions of plants cells with 3D bioprinting

Fluctuating oxygen levels could have accelerated the development of early animal life

Widespread variations in retroviral establishment and distribution among Darwin's finches

Newly identified process keeps some immune cells on their toes

Pain-sensing neurons protect the gut from inflammation and associated tissue damage

Study determines how fibroblasts play a role in tumor's ability to generate anti-HER2 therapy resistance

Rheumatoid arthritis drug can be repurposed to improve diabetes-associated symptoms

SARS-CoV-2 causes neuronal damage and inflammation within a week of infection in rhesus macaques

New noninvasive neuroimaging method for direct mapping of neuronal activity in a living mouse's brain

Small solutions for big problems in drug discovery and delivery

Professor Nancy Ip: Pioneering New Paths in Neurodegenerative Therapy

Utilizing process Raman in optimizing cultivated meat production

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