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Study reveals the molecular mechanisms of dynamic activation of DNMT1 by H3Ub2

This study is led by Dr. Na Yang (State Key Laboratory of Medicinal Chemical Biology, College of Pharmacy and Key Laboratory of Medical Data Analysis and Statistical Research of Tianjin, Nankai University), and Dr. Bing Zhu (National Laboratory of Biomacromolecules, CAS Center for Excellence in Biomacromolecules, Institute of Biophysics, Chinese Academy of Science).

28 Oct 2022

Piceatannol and mTOR inhibitor combination proves be an attractive therapeutic strategy for gastric cancer

This study is led by Dr. Longtao Huangfu, and Dr. Xiaoyang Wang (Peking University Cancer Hospital & Institute). A diet of fresh fruits and vegetables may reduce the prevalence of cancers, including GC (Eusebi et al., 2020; Liu et al., 2021).

28 Oct 2022

Faulty gene may explain why some people gain excessive weight despite normal food intake

A faulty gene, rather than a faulty diet, may explain why some people gain excessive weight even when they don't eat more than others, UT Southwestern researchers at the Center for the Genetics of Host Defense have discovered.

28 Oct 2022

Ceria nanoparticles interfere with biological processes just like native enzymes

Bacteria love moist surfaces. Once they have settled there, they do not live as solitary organisms but form larger communities that are embedded in a protective film.

28 Oct 2022

Researchers propose origin-of-life molecule as therapeutic target for tailored cancer therapies

RNA, the molecule that gave rise to life, has been shown to be essential for repairing human genetic material and preventing mutations that might lead to developing cancer.

28 Oct 2022

Cancer cells' sticky fingers contribute to building a barrier surrounding breast tumors

Researchers at Turku University and Åbo Akademi University, Finland, have identified that finger-like cellular extensions called filopodia contribute to building a barrier surrounding breast tumors.

28 Oct 2022

Research shows in real time how immune memory cells are stored in the bone marrow

Vaccines work their magic by effectively creating immune cells that are long lived, often for over decades.

28 Oct 2022

Yeast reveals a key mechanism in how genes are controlled

Yeast, that simple organism essential to making beer and bread, has revealed for Cornell University researchers a key mechanism in how genes are controlled.

28 Oct 2022

New breakthrough in understanding how deletion of certain genes can lead to cancer growth

Genetic mutations kick start cancers. Some mutations shuffle the genetic code, others come from the deletion of key genes.

28 Oct 2022

Proof-of-principle study: Novel tool advances potential way to deliver gene therapy

Johns Hopkins Medicine researchers say they have successfully used a cell's natural process for making proteins to "slide" genetic instructions into a cell and produce critical proteins missing from those cells.

28 Oct 2022

Researchers unravel the precise mechanism of nuclear envelope repair in human and mouse cells

All living cells harbor nuclei-;key biological structures that play an important role in information storage, retrieval, and duplication of genetic information.

28 Oct 2022

Ancient viral DNA in human genomes protects cells against present-day viruses

Viral DNA in human genomes, embedded there from ancient infections, serve as antivirals that protect human cells against certain present-day viruses, according to new research.

27 Oct 2022

Newly developed chemical compounds show promise as potential anticancer therapy

A University of Kentucky Markey Cancer Center researcher's team developed new chemical compounds that show promise as a potential anticancer therapy to treat aggressive tumors.

27 Oct 2022

RNA-sensing platform could help detect and selectively kill tumors, or edit the genome in specific cells

Researchers at the Broad Institute of MIT and Harvard and the McGovern Institute for Brain Research at MIT have developed a system that can detect a particular RNA sequence in live cells and produce a protein of interest in response.

27 Oct 2022

New study pinpoints neurons that slow us down during sickness

We tend to eat, drink, and move less when we're feeling under the weather. And we're not alone-;most animals reduce those same three behaviors when they're fighting an infection.

27 Oct 2022

Using stem cell cloning to identify the origin of lethal stomach and esophageal cancers

The University of Houston is leading a team of cancer researchers and experts in stem cell cloning to identify the origin of two very lethal cancers of the stomach and esophagus - esophageal adenocarcinoma (EAC) and intestinal gastric cancer (iGC).

27 Oct 2022

Researchers find a switch to regulate the diabetes-causing gene

Researchers at the Centre for Genomic Regulation and Imperial College London have found a switch that regulates the activity of a gene that causes diabetes.

27 Oct 2022

Increased Gibbs energy of binding indicates greater infectivity of SARS-CoV-2 BA.2.75

Researchers explore the thermodynamic properties of the SARS-CoV-2 Omicron subvariant BA.2.75 to understand its increased transmissibility.

27 Oct 2022

New discovery may change the textbook model of GPCR-mediated signaling

Researchers at University of California San Diego have identified a new signaling process involving G protein-coupled receptors (GPCRs), a cellular target already exploited by hundreds of diverse drugs.

27 Oct 2022

Research reveals molecular pathways of aggressive cribriform prostate cancer

Cribriform prostate cancer is an aggressive subtype of the disease characterized by its histology, but little is known about its molecular pathways.

26 Oct 2022

Life Science News

Study reveals the molecular mechanisms of dynamic activation of DNMT1 by H3Ub2

Piceatannol and mTOR inhibitor combination proves be an attractive therapeutic strategy for gastric cancer

Faulty gene may explain why some people gain excessive weight despite normal food intake

Ceria nanoparticles interfere with biological processes just like native enzymes

Researchers propose origin-of-life molecule as therapeutic target for tailored cancer therapies

Cancer cells' sticky fingers contribute to building a barrier surrounding breast tumors

Research shows in real time how immune memory cells are stored in the bone marrow

Yeast reveals a key mechanism in how genes are controlled

New breakthrough in understanding how deletion of certain genes can lead to cancer growth

Proof-of-principle study: Novel tool advances potential way to deliver gene therapy

Researchers unravel the precise mechanism of nuclear envelope repair in human and mouse cells

Ancient viral DNA in human genomes protects cells against present-day viruses

Newly developed chemical compounds show promise as potential anticancer therapy

RNA-sensing platform could help detect and selectively kill tumors, or edit the genome in specific cells

New study pinpoints neurons that slow us down during sickness

Using stem cell cloning to identify the origin of lethal stomach and esophageal cancers

Researchers find a switch to regulate the diabetes-causing gene

Increased Gibbs energy of binding indicates greater infectivity of SARS-CoV-2 BA.2.75

New discovery may change the textbook model of GPCR-mediated signaling

Research reveals molecular pathways of aggressive cribriform prostate cancer

Small solutions for big problems in drug discovery and delivery

Professor Nancy Ip: Pioneering New Paths in Neurodegenerative Therapy

Utilizing process Raman in optimizing cultivated meat production

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