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Genetic variants linked with risk tolerance and risky behaviors

As part of an international research project, a group of scientists from the University of Zurich found genetic variants associated with risk tolerance and risky behaviors. It is one of the first studies to link genetic variants with behavioral outcomes, which are relevant to social science research.

14 Jan 2019

Plan your Pittcon 2019 with the mobile app

The Pittcon marketing department is excited to announce the release of its official conference and exposition mobile app, Pittcon 2019.

From Pittcon 14 Jan 2019

Scientists discover mutational signatures of tumor hypoxia

Researchers have discovered mutational signatures of tumor hypoxia in 19 cancer types that could be used to identify patients who need higher treatment doses.

14 Jan 2019

New discovery casts doubt on plasma membrane models

Like planets, the body's cell surfaces look smooth from a distance but hilly closer up. An article published in Communications Biology describes implications, unknown to date, of the way data from cell surfaces are normally interpreted; i.e. as if they lacked topographic features.

14 Jan 2019

Conducting ChIP-Seq with Low Cell Numbers

An interview with Dr. Kathyrn Cunningham at SfN 2018, providing advice on carrying out Chromatin Immunoprecipitation Sequencing (ChIP-seq) with low cell numbers.

From Active Motif 14 Jan 2019

Researchers repurpose gene-editing tool CRISPR to develop better antibiotics

A University of Wisconsin-Madison researcher and his collaborators at the University of California, San Francisco have repurposed the gene-editing tool CRISPR to study which genes are targeted by particular antibiotics, providing clues on how to improve existing antibiotics or develop new ones.

11 Jan 2019

Novel microfluidic device for real-time detection of cholesterol in liver-on-chip cultures

In a paper to be published in the September/December 2019 issue of TECHNOLOGY, a team of researchers from the Department of Biomedical Engineering at Illinois Institute of Technology, Chicago has developed a novel microfluidic device for measuring in real-time the cholesterol secreted from liver tissue-chip containing human hepatocytes.

11 Jan 2019

Fluorescence Microscopy: Choosing the Right lllumination System

In this interview from SfN 2018, Michelle Gal explains the fluorescence illumination systems for fluorescence microscopy, offered by Excelitas technologies.

From Excelitas Technologies 11 Jan 2019

Bio-Rad publishes new paper on generation, characterization of complex-specific antibodies

Bio-Rad Laboratories, Inc., a global leader of life science research and clinical diagnostic products, has published new findings on the generation and characterization of drug-target complex-specific antibodies for pharmacokinetic analysis of biotherapeutics.

From Bio-Rad Laboratories 11 Jan 2019

CRISPR-Cas9 circular permutants can sense and respond to viral proteases

Using a technique called circular permutation, researchers at the University of California Berkeley have created a new suite of Cas9 variants called Cas9-CPs, which will simplify design of Cas9-fusion proteins for diverse applications beyond simple DNA cutting, such as base editing and epigenetic modifications.

11 Jan 2019

New method modifies blood stem cells to reverse genetic mutation that causes IPEX

UCLA researchers led by Dr. Donald Kohn have created a method for modifying blood stem cells to reverse the genetic mutation that causes a life-threatening autoimmune syndrome called IPEX.

11 Jan 2019

New generation of chemists conducts research to further understand complex nature of lipids

The post-holiday New Year might not seem like an ideal time to celebrate fat. But when it comes to lipids, there is no better time.

11 Jan 2019

Steady-state CD spectroscopy is a major structural tool in (bio)chemical analysis

In nature, certain molecules with the same chemical composition, can exist in two different shapes that are mirrors images of each other, much like our hands.

11 Jan 2019

Defective astrocytes linked to alpha-synuclein accumulation in Parkinson's

Researchers have found that defects in brain glial cells called astrocytes are linked to the accumulation of alpha-synuclein in Parkinson's disease.

10 Jan 2019

Researchers identify promising therapeutic option to treat multiple sclerosis

Researchers at the Medical Center of Johannes Gutenberg University Mainz (JGU) identified an innovative and promising therapeutic option to treat multiple sclerosis.

10 Jan 2019

Unusual molecular regulatory mechanism discovered in unicellular parasites

Researchers of the University of Bern have discovered a new molecular regulatory mechanism in unicellular parasites which has never before been observed.

10 Jan 2019

New certified reference material for testing residual solvents in cannabis

This new certified reference material from Restek contains 20 commonly analyzed residual solvents in one convenient solution.

From Restek Corporation 10 Jan 2019

High-performing MS device reaches new level in characterizing protein impurities

In response to current regulatory guidance a Mass Spectrometry-based Host Cell Protein detection approach with faster, more accurate and wider-ranging detection is essential.

10 Jan 2019

Bacteria on the International Space Station are adapting to survive, not to harm

Mutant bacteria stranded in space by visiting astronauts have been adapting to survive in their new environment, according to a new study.

10 Jan 2019

Study explains why some drugs work well in ameliorating side effects of chemotherapy

Researchers at the University of Zurich have determined the three-dimensional structure of the receptor that causes nausea and vomiting as a result of cancer chemotherapy.

10 Jan 2019

Life Science News

Genetic variants linked with risk tolerance and risky behaviors

Plan your Pittcon 2019 with the mobile app

Scientists discover mutational signatures of tumor hypoxia

New discovery casts doubt on plasma membrane models

Conducting ChIP-Seq with Low Cell Numbers

Researchers repurpose gene-editing tool CRISPR to develop better antibiotics

Novel microfluidic device for real-time detection of cholesterol in liver-on-chip cultures

Fluorescence Microscopy: Choosing the Right lllumination System

Bio-Rad publishes new paper on generation, characterization of complex-specific antibodies

CRISPR-Cas9 circular permutants can sense and respond to viral proteases

New method modifies blood stem cells to reverse genetic mutation that causes IPEX

New generation of chemists conducts research to further understand complex nature of lipids

Steady-state CD spectroscopy is a major structural tool in (bio)chemical analysis

Defective astrocytes linked to alpha-synuclein accumulation in Parkinson's

Researchers identify promising therapeutic option to treat multiple sclerosis

Unusual molecular regulatory mechanism discovered in unicellular parasites

New certified reference material for testing residual solvents in cannabis

High-performing MS device reaches new level in characterizing protein impurities

Bacteria on the International Space Station are adapting to survive, not to harm

Study explains why some drugs work well in ameliorating side effects of chemotherapy

Small solutions for big problems in drug discovery and delivery

Professor Nancy Ip: Pioneering New Paths in Neurodegenerative Therapy

Utilizing process Raman in optimizing cultivated meat production

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