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Researchers find how NF2 gene mutations lead to out-of-control cellular proliferation

A team of Massachusetts General Hospital Cancer Center researchers has determined one way that mutations in a gene involved in a rare, hereditary cancer syndrome lead to out-of-control cellular proliferation.

29 Aug 2018

New technique for mapping flow of biomolecules in tumor microenvironment

Cancer researchers struggle to identify tumor cells that are interspersed within nonmalignant tissues because tumor cells exploit the tissue environment and monopolize available resources to continue growing.

29 Aug 2018

Researchers enlist genes that control production of cellular energy stored in ATP molecules

Everything the body does--your brain thinking, your heart beating, your cells growing--requires energy. Consequently, it comes as no surprise that disruptions in energy production can contribute to a wide range of diseases.

29 Aug 2018

Scientists reveal novel brain network linked to pain in Parkinsonism

Scientists have revealed a novel brain network that links pain in Parkinson's disease (PD) to a specific region of the brain, according to a report in the journal eLife.

28 Aug 2018

Pediatric researchers discover gene mutation that causes lymphatic disorder

Pediatric researchers have identified a gene mutation that causes a serious lymphatic condition, and used that knowledge to restore normal lymphatic vessels in model animals. The laboratory findings may lead to a new therapy for patients with this type of abnormal lymphatic circulation.

28 Aug 2018

Researchers report how Zika proteins hijack host cells

Most people infected with Zika never show symptoms. But the virus sometimes causes severe disability -- from microcephaly in babies to weakness or partial paralysis in adults -- and there is no treatment.

28 Aug 2018

Protein modifications that indicate disease

Researchers from the University of Zurich can, for the first time, precisely characterize the protein modification ADP-ribosylation for all proteins in a tissue sample.

28 Aug 2018

Researchers develop 3D map of the human genome

Researchers have developed a way of mapping the positions of genes within cells to understand more about how the genome is organized.

28 Aug 2018

International research effort yields 'Image-Activated Cell Sorting' technology

Invented over 50 years ago, flow cytometry-based cell sorting has become a widely used tool in biology labs for physically isolating cells based on their global surface marker expression profiles.

28 Aug 2018

Porvair Sciences' UltraJet pipette filler is perfect for use in confined spaces

Compact in size, the UltraJet electronic pipette filler from Porvair Sciences is perfect for use even in confined spaces such as safety cabinets and fume hoods. The UltraJet pipette filler is quick and simple to operate. Its lightweight, ergonomic design ensures you can use it for extended periods of time without discomfort.

From Porvair Sciences Limited 28 Aug 2018

NRGene constructs comprehensive soy genome diversity-haplotype database

NRGene, the leading genomic big data company, has constructed a comprehensive soy genome diversity-haplotype database based on results from GenoMAGIC™, allowing commercial and academic researchers never-before-available insights into the genomic diversity within the soybean crop.

28 Aug 2018

INTEGRA’s electronic pipettes simplify work in GLP environments

Which brand of pipette to use may not be your first consideration when designing your laboratory workflows and SOPs to follow good laboratory practice, but choosing the right pipette can make it much easier to achieve consistent results.

From INTEGRA Biosciences 28 Aug 2018

Scientists introduce bioinspired enzyme model with redox switch

Coupled oxygen transfer and electron transfer reactions that use cofactors are enzymatic reactions of crucial significance to all lifeforms from bacteria to vertebrates. In the European Journal of Inorganic Chemistry, scientists have introduced a model for the enzyme sulfite oxidase.

28 Aug 2018

Research solves mystery on nature of EGFR signaling and how it drives development

What do cancer and the growing legs of a fruit fly have in common? They can both be influenced by a single molecule, a protein that tends to call the shots inside of embryos as they develop into living, breathing animals.

28 Aug 2018

NorthShore University HealthSystem highlights utility of Streck ARM-D Kits for antimicrobial resistance detection

Streck, Inc., received great interest for Streck ARM-D Kits, used in the detection of antibiotic resistance, at ASM Microbe 2018 in Atlanta.

28 Aug 2018

Pancreas' network of enzyme ducts resembles formation of rivers

With methods used to analyze road systems and rivers researchers from the University of Copenhagen have studied the formation of the pancreas' network of ducts transporting digestive enzymes in mice.

27 Aug 2018

Discovery will allow scientists to target hypoxia in cancer

Researchers have discovered a new GPCR that will allow them to target hypoxia in cancer, offering a new, less harmful treatment for patients.

27 Aug 2018

Study sheds light on how cholera became a human pathogen

Scientists think they may have discovered how V. cholerae became a human pathogen, through its ability to interact with amoebae in aquatic environments.

27 Aug 2018

Changes in TRPV3 genes may have helped mammoths withstand lower temperatures

Columbia University biomedical researchers have captured close-up views of TRPV3, a skin-cell ion channel that plays important roles in sensing temperature, itch, and pain.

25 Aug 2018

Researchers identify series of molecules involved in regeneration of damaged nerves

Researchers at Nagoya University have identified the series of molecules involved in the regeneration of damaged nerves in roundworm, showing that it largely overlaps with the signals used by the intrinsic removal system to take up and process dying cells.

24 Aug 2018