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Breakthrough study sheds light on mechanism underlying Warsaw Breakage Syndrome

Researchers from Tokyo Metropolitan University and the FIRC Institute of Molecular Oncology in Italy have uncovered a previously unknown function of the DDX11 helicase enzyme.

3 Sep 2018

Restricting food to 10-hour window can lead to better health

Scientists at the Salk Institute found that mice lacking the biological clocks thought to be necessary for a healthy metabolism could still be protected against obesity and metabolic diseases by having their daily access to food restricted to a 10-hour window.

31 Aug 2018

A genetic signal-transmission system for the gut microbiome

More than 1,000 species of bacteria have been identified in the human gut, and understanding this incredibly diverse "microbiome" that can greatly impact health and disease is a hot topic in scientific research.

31 Aug 2018

Scientists shed light on how dangerous inflammations are caused in the brain

The so-called CB1 receptor is responsible for the intoxicating effect of cannabis. However, it appears to act also as a kind of “sensor” with which neurons measure and control the activity of certain immune cells in the brain.

31 Aug 2018

UQ researchers discover new immune defense pathway deployed against bacteria

A new understanding of one of the body’s immune defense mechanisms could lead to the development of novel therapeutic targets for conditions such as cancer and autoimmune diseases, a University of Queensland study has revealed.

31 Aug 2018

Cryptosporidiosis worsened by commonly used probiotic

Researchers have found that infection with the intestinal parasite Cryptosporidium parvum is worsened in mice that have been administered a probiotic.

31 Aug 2018

Modified Nurr1 protein may pave way for new Parkinson's therapy

Researchers have modified the protein Nurr1 so that it can enter cells from the outside. Nurr1 deficiency may be one of the causes of Parkinson's disease.

31 Aug 2018

Researchers predict how splicing errors impact disease risk

No one knows how many times in a day, or even an hour, the trillions of cells in our body need to make proteins.

31 Aug 2018

UTA scientists map function of enzymes to provide keys for developing new drugs

UTA biochemists are mapping the function of specific enzymes which may facilitate development of new drugs to fight bacterial infection, cancer and potentially neurodegenerative diseases like autism, Down syndrome, Parkinson's disease and Alzheimer's.

30 Aug 2018

Fluorescent protein sensor detects changes in cellular oxygen levels with very high sensitivity

Based on a protein from E. coli, scientists at Tokyo Institute of Technology have developed a fluorescent protein sensor able to provide real-time information on dynamic changes in oxygen levels with very high sensitivity.

30 Aug 2018

Researchers provide new virulence clues through genomic study of anthrax strains

By analyzing genomic sequences from more than 400 strains of the bacterium that causes anthrax, researchers have provided the first evidence that the severity - technically known as virulence - of specific strains may be related to the number of copies of certain plasmids they carry.

30 Aug 2018

Celmatix and Ferring announce genomics collaboration aimed at uncovering new insights into ovarian biology

Ferring Pharmaceuticals and Celmatix today announced an ambitious genomics collaboration aimed at uncovering new insights into ovarian biology and accelerating the development of personalized interventions in reproductive medicine and women's health.

30 Aug 2018

Modified T lymphocytes prevent nerve cell damage in encephalitis

Scientists have found a way to prevent neuron death in Rasmussen’s encephalitis, by exploiting T lymphocytes in the immune system.

30 Aug 2018

Vertex, Genomics team up to improve discovery of precision medicines

Vertex Pharmaceuticals Incorporated (Nasdaq: VRTX) and Genomics plc today announced a three-year collaboration, extendable to five years, to use human genetics and machine learning to improve discovery of targets for precision medicines, and to advance understanding of the clinical impact of human genetic variation and patient stratification in diseases with significant unmet need.

30 Aug 2018

Small black box could change the way scientists search for new antibiotics

A small, black box developed in a McMaster University lab could change the way scientists search for new antibiotics.

30 Aug 2018

Scientists explore DNA replication errors that can lead to cancer

Scientists at Hollings Cancer Center at the Medical University of South Carolina have found that some cells can divide without a molecule that was previously thought necessary.

30 Aug 2018

Scientists regenerate nerve fibers after spinal cord injury

Scientists have discovered the biological mechanisms needed for nerve fibers to regenerate in spinal cord injury.

29 Aug 2018

Research shows proteomics can be used to predict evolution of triple negative breast cancer

The rarest, but also the most aggressive and hard to treat form of breast cancer, is known as triple negative. For this type of cancer, researchers have so far been unable to identify markers that can classify patients by prognosis or probability of responding to different treatments.

29 Aug 2018

Cherwell confirms support for conference addressing key challenges in aseptic manufacturing of ATMPs

Cherwell Laboratories, supplier of environmental monitoring and process validation products, has confirmed its continued support for the Pharmaceutical & Healthcare Sciences Society - UCL Q3P Annual Conference 2018.

29 Aug 2018

Protein aggregates may play protection role against toxic stresses

Protein aggregates have a bad reputation in conditions such as Alzheimer’s disease and Parkinson’s disease, but in bacteria, inheritance of aggregates by daughter cells may help protect against the same toxic stresses that triggered them in parental cells, according to a new study publishing 28 August in the open access journal PLOS Biology, by Sander Govers, Abram Aertsen, and colleagues at KU Leuven, Belgium.

29 Aug 2018