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Genomic markers can predict lynch syndrome across tumor types

Microsatellite instability and DNA mismatch repair deficiencies can predict Lynch syndrome across tumor types, according to researchers from Memorial Sloan Kettering Cancer Center, who presented this retrospective data analysis in a press conference at the annual meeting of the American Society of Clinical Oncology.

4 Jun 2018

Researchers use magnets to control tiny DNA-based robots

Researchers have devised a magnetic control system to make tiny DNA-based robots move on demand-;and much faster than recently possible.

4 Jun 2018

Detailed structure of protein pair offers blueprint for new medicines

Walter and Eliza Hall Institute researchers have visualized for the first time how the protein SOCS1 'switches off' cell signaling to dampen immune responses and block cancer growth.

4 Jun 2018

Free-floating DNA analysis test may help detect early-stage lung cancer

A test that analyzes free-floating DNA in the blood may be able to detect early-stage lung cancer, a preliminary report from the ongoing Circulating Cell-Free Genome Atlas study suggests.

4 Jun 2018

Researchers develop novel microscopy to observe cellular focal adhesion dynamics

Focal adhesions are large specialized proteins that are located in the area where a cell membrane meets the extracellular matrix, a collection of molecules surrounding the cells that provide support and regulate micromechanical signals to the cells.

4 Jun 2018

MD Anderson and Amgen collaborate to accelerate early-stage oncology therapies

The University of Texas MD Anderson Cancer Center and Amgen today announced two multi-year collaboration agreements aimed at accelerating development of a variety of Amgen's early-stage oncology therapies for patients with leukemia, myelodysplastic syndromes, multiple myeloma, small-cell lung cancer, and other non-lung cancers with small-cell histologies.

1 Jun 2018

Novel microscope technology offers images of the brain with 4K resolution and 3D visualization

The Department of Neurosurgery at the Icahn School of Medicine at Mount Sinai is one of the first hospitals in the country to use the ZEISS KINEVO 900 microscope, a new surgeon-driven, robotic visualization system that merges the functionality of a surgical microscope with 4K resolution and 3D visualization along with specialized robotic control.

1 Jun 2018

UK scientists 3D-print the first human corneas

For the first time in history, scientists from have 3D-printed human corneas, providing a potential solution to the current shortage of corneas for transplant.

1 Jun 2018

Discovering Antibodies with Universal Specificity

Professor Hedda Wardemann discusses our current knowledge of antibody specificity and how her research team are challenging this, through the discovery of anti-bacterial antibodies with universal specificity.

1 Jun 2018

Salk researchers discover molecule that destroys key HIV protein

One of the many challenges in treating HIV is that the virus can lie dormant in cells, quietly evading immune detection until it suddenly roars to life without warning and begins replicating furiously.

1 Jun 2018

Researchers discover three genes that may have contributed to evolution of large human brain

Three genes involved in nerve cell generation in the brain emerged roughly 3.5 million years ago and may have contributed to the rapid evolution of the large human brain, Howard Hughes Medical Institute (HHMI) Investigator David Haussler and colleagues report on May 31, 2018, in the journal Cell.

1 Jun 2018

Study reveals 133 genetic variants that may improve risk prediction for glaucoma

Researchers funded by the National Eye Institute have identified 133 genetic variants that predict with 75-percent accuracy a person's risk for developing glaucoma related to elevated pressure within the eye.

31 May 2018

Research sheds light on genetic characteristics of Indonesia's rotavirus

Rotavirus A causes acute diarrhea in young children, and infects both animals and humans worldwide. A Japanese research group has found that the acute gastroenteritis infecting children in Indonesia between 2015 and 2016 was caused by dominant strains of equine-like G3 rotavirus, genetically different from human strains of the virus.

31 May 2018

New technique provides more direct way to discern what microbes consume

A new technique devised by researchers from North Carolina State University and the University of Calgary provides a more in-depth look at the metabolism and physiology within microbial communities - the microscopic life such as bacteria, viruses and other tiny forms of life within our bodies and throughout nature.

31 May 2018

Highly stable DNA origami nanostructures may pave way for a plethora of biomedical applications

The DNA origami technique is a widely used method for making complex, yet well-defined nanostructures, with applications in biophysics, molecular biology, as well as drug and enzyme delivery.

31 May 2018

Study: Cellular housekeeping can help mammals live longer and healthier

Building on two decades of research, investigators at UT Southwestern have determined that "cellular housekeeping" can extend the lifespan and healthspan of mammals.

31 May 2018

Study: Disease-causing stomach bacterium shuts down energy production in host cells

Researchers report in a new study that the bacterium Helicobacter pylori - a major contributor to gastritis, ulcers and stomach cancer - resists the body's immune defenses by shutting down energy production within the cells of the stomach lining that serve as a barrier to infection.

31 May 2018