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Discovery of unusual biosynthetic pathways could aid in the search for new natural products

Bacteria are master engineers of small, biologically useful molecules. A new study in Nature Communications has revealed one of the tricks of this microbial trade: synthesizing and then later inserting a nitrogen-nitrogen bond, like a prefabricated part, into a larger molecule.

12 Sep 2018

Study opens up new possibilities for designing novel medicines

A study by the Computational Biochemistry Research Group of the Universitat Jaume I of Castellón, Spain, shows that enzyme activity depends on electrostatic properties, as opposed to mechanical ones.

11 Sep 2018

Scientists develop first DNA-based test for predicting risk of leukemia relapse

A group of Canadian and Korean scientists and physicians have developed the first DNA-based test that allows them to tell which patients will relapse after receiving chemotherapy and a bone marrow transplant, for their acute myeloid leukemia, or AML.

11 Sep 2018

How 'bad' bacteria gain an upper hand in the human gut

A study has revealed that the bacterium C. difficile gains a competitive advantage over protective bacteria in the human gut by producing para-cresol.

11 Sep 2018

Improve reliability, accuracy of drug discovery process with new 3D cell analysis technology

Olympus Corporation today announced the U.S.-only launch of a new 3D cell analysis technology with ability to accurately analyze 3D cell cultures down to the nuclei, improving the reliability and accuracy of the entire drug discovery process, from compound selection to animal experimentation and clinical trials in humans.

From Evident Corporation - Life Sciences 11 Sep 2018

Phasefocus launches new corporate website

Phasefocus is delighted to announce the launch of a new corporate website. With a fresh look and feel, the new site has been designed to improve the end-user experience, providing simple, logical, navigation, allowing visitors to rapidly locate and access a wealth of product and application information from a single location.

From Phase Focus Limited 11 Sep 2018

MILabs' new Broadband Photon Tomography selected for Innovation of the Year award

MILabs is pleased to announce that its new Broadband Photon Tomography technique has been nominated for the Innovation of the Year 2018 award by the World Molecular Imaging Society (WMIS) board of trustees.

11 Sep 2018

Tecan offers insights on automated liquid handling platform usage with connected laboratory automation

Tecan is offering its customers unprecedented insight into how their Fluent and Freedom EVO liquid handing platforms are being used, thanks to its Introspect and Common Notification System software tools.

From Tecan 11 Sep 2018

Uniqsis introduces Polar Bear Plus GSM reactor for flow chemistry applications

Uniqsis has introduced the Polar Bear Plus GSM - a versatile heating and cooling reactor module for flow chemistry applications using Glass Static Mixers / Reactor Chips.

From Uniqsis Ltd 11 Sep 2018

Measuring nanocrystal length and thickness in just 40 minutes analysis time

Postnova Analytics reports on how Asymmetrical Flow Field Flow Fractionation coupled to Multi Angle Light Scattering (AF4-MALS) has been successfully used to characterize a polydisperse cellulose nanocrystal for size and thickness in just 40 minutes analysis time.

From Postnova Analytics 11 Sep 2018

Improving environmental impact in materials science discovery laboratories

Asynt reports how the Rannard Group at the Materials Innovation Factory, at the University of Liverpool (UK), uses new technologies supplied by the company to help improve the environmental impact and reduce water and electrical consumption within their materials science discovery laboratories.

From Asynt 11 Sep 2018

Molecular switches are far more complex than previously assumed

The GTPases constitute a very large protein family, whose members are involved in the control of cell growth, transport of molecules, synthesis of other proteins, etc. Despite the many functions of the GTPases, they follow a common cyclic pattern.

10 Sep 2018

BAP1 protein serves as tumor suppressor gene in kidney, eye, bile duct and mesothelioma cancers

Researchers at The University of Texas MD Anderson Cancer Center have shown how BRCA-associated protein 1 (BAP1) serves as a tumor suppressor gene in kidney, eye, bile duct, mesothelioma and other cancers by regulating a form of cell death called ferroptosis, opening up a potential new area of therapy research.

10 Sep 2018

New framework combines three existing methods to find cancer cell mutations

Cancer cells often have mutations in their DNA that can give scientists clues about how the cancer started or which treatment may be most effective. Finding these mutations can be difficult, but a new method may offer more complete, comprehensive results.

10 Sep 2018