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Determining the Optimal Biomarker Frequency for Biosensors

Chi-En Lin won Metrohm’s Young Chemist of the Year award for research into optimal biomarker frequencies and how it can be applied.

From Metrohm USA Inc. 22 May 2018

DNA vaccine shows promise for colorectal cancer

For the first time in humans, researchers are testing a combined approach to treating advanced stage colorectal cancer (CRC) that may be life-changing for patients.

22 May 2018

Scientists decipher workings of little-understood bacterial riboswitch

In a discovery that points to potential new antibiotic medicines, scientists from Rice University and the University of Michigan have deciphered the workings of a common but little-understood bacterial switch that cuts off protein production before it begins.

22 May 2018

Researchers discover unexpected chemosensor pathway for predator odor-evoked innate fear behaviors

Innate fear is an essential emotion for animals to avoid danger in a severe natural environment. Rodents kept in a laboratory also show instinctive fear behavior against the smell of predators such as foxes, cats or snakes despite having never seen them.

22 May 2018

Novel drug prevents memory impairment in mice exposed to simulated deep space radiation

Planning a trip to Mars? You'll want to remember your anti-radiation pills. NASA and private space companies like SpaceX plan to send humans to the red planet within the next 15 years--but among the major challenges facing future crewed space missions is how to protect astronauts from the dangerous cosmic radiation of deep space.

22 May 2018

CRISPR-Cas9-based strategy allows researchers to precisely alter hundreds of different genes

Geneticists have been using model organisms ranging from the house mouse to the single-cell bakers' yeast, Saccharomyces cerevisiae, to study basic biological processes that regulate human development and physiology, and that can be compromised in various diseases.

22 May 2018

Scientists identify cell types underlying schizophrenia

Scientists at Karolinska Institutet in Sweden and University of North Carolina, USA, have identified the cell types underlying schizophrenia in a new study published in Nature Genetics. The findings offer a roadmap for the development of new therapies to target the condition.

21 May 2018

Neurological protein found to protect against inflammatory diseases

Researchers have identified a protein involved in the activation of macrophages that protects against inflammatory disorders such as sepsis and inflammatory bowel disease.

21 May 2018

Scientists collate evidence for mismatch between past evolutionary adaptation and modern lives

The transition to modernity - largely driven by the Industrial Revolution - provided us with easier access to food and clean water, with antibiotics, vaccines, and modern medicine.

21 May 2018

Researchers identify protein essential for eye lens development and clear vision

If you want to take clear photographs, you don't use sandpaper to clear a smudge from your camera's lens. Similarly, if you want to see clearly, the lens of your eye has to be free of obstruction.

21 May 2018

Flow of cerebrospinal fluid found to be key signal for neural stem cell renewal

Stem cells in the brain can divide and mature into neurons participating in various brain functions, including memory.

21 May 2018

Study brings fresh insights into biology of malaria parasite

A team of researchers led by a University of California, Riverside, scientist has found that various stages of the development of human malaria parasites, including stages involved in malaria transmission, are linked to epigenetic features and how chromatin -- the complex of DNA and proteins within the nucleus -- is organized and structured in these parasites.

18 May 2018

Study offers novel solution to suppress metastatic spread of deadly breast cancer

USC researchers have pinpointed a remedy to thwart a protein that helps the metastatic spread of breast cancer, a leading cause of death for women. The findings appear today in Nature Communications.

18 May 2018

New CRISPR/Cas9 system targets regulatory genes of AIDS virus

By destroying the regulatory genes of the AIDS virus HIV-1 using the genome editing system CRISPR/Cas9, a Japanese research group has succeeded in blocking the production of HIV-1 by infected cells.

18 May 2018

Whole genome sequencing could prevent transfusion reactions

Researchers have recently published a study which may reduce complications and save lives for blood transfusion recipients.

18 May 2018

Researchers uncover unusual form of cross-talk between proteins that affect gene expression

Turning genes on and off is an intricate process involving communication between many different types of proteins that interact with DNA.

18 May 2018

Developing a High Throughput Mass Spectrometry Platform for Drug Discovery

Prof. Jonathan Wingfield, AstraZeneca, describes the collaboration with Labcyte and Waters to develop a high throughput mass spectrometry platform.

From Pittcon 18 May 2018

Lizards with bright green blood baffle scientists

A species of lizards has been found to have bright green blood. Researchers in their study published this Tuesday said that this finding could provide understanding in illnesses such as malaria and jaundice. The study was published in Science Advances.

17 May 2018

Study provides insights into how immune cells kill bacteria with acid

The first line of immune defense against invading pathogens like bacteria are macrophages, immune cells that engulf every foreign object that crosses their way. After enclosing it in intracellular membrane vesicles, a process called phagocytosis, macrophages kill their prey with acid.

17 May 2018

AstraZeneca collaborates with Emulate to integrate Organs-on-Chips technology into drug development labs

Emulate, Inc. has formed a collaborative partnership with AstraZeneca’s Innovative Medicines and Early Development Biotech Unit to embed its Organs-on-Chips technology within the laboratories of the IMED Drug Safety organization.

From AstraZeneca 17 May 2018

Life Science News

Determining the Optimal Biomarker Frequency for Biosensors

DNA vaccine shows promise for colorectal cancer

Scientists decipher workings of little-understood bacterial riboswitch

Researchers discover unexpected chemosensor pathway for predator odor-evoked innate fear behaviors

Novel drug prevents memory impairment in mice exposed to simulated deep space radiation

CRISPR-Cas9-based strategy allows researchers to precisely alter hundreds of different genes

Scientists identify cell types underlying schizophrenia

Neurological protein found to protect against inflammatory diseases

Scientists collate evidence for mismatch between past evolutionary adaptation and modern lives

Researchers identify protein essential for eye lens development and clear vision

Flow of cerebrospinal fluid found to be key signal for neural stem cell renewal

Study brings fresh insights into biology of malaria parasite

Study offers novel solution to suppress metastatic spread of deadly breast cancer

New CRISPR/Cas9 system targets regulatory genes of AIDS virus

Whole genome sequencing could prevent transfusion reactions

Researchers uncover unusual form of cross-talk between proteins that affect gene expression

Developing a High Throughput Mass Spectrometry Platform for Drug Discovery

Lizards with bright green blood baffle scientists

Study provides insights into how immune cells kill bacteria with acid

AstraZeneca collaborates with Emulate to integrate Organs-on-Chips technology into drug development labs

Small solutions for big problems in drug discovery and delivery

Professor Nancy Ip: Pioneering New Paths in Neurodegenerative Therapy

Utilizing process Raman in optimizing cultivated meat production

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