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Researchers discover key inner control mechanism of cell's 'smart glue'

Researchers at St. Jude Children's Research Hospital have discovered that a protein critical to a process called liquid-liquid phase separation within the cell undergoes internal changes in conformation that are key to its function.

26 Feb 2018

Hamilton Robotics Launch ID NIMBUS® for Forensic Genomics Applications

Hamilton Robotics announce the release of the ID NIMBUS® assay ready workstation, specifically pre-configured and qualified to automate post-PCR sample processing using the Verogens renowned ForenSeq DNA Signature Prep Kit.

From Hamilton Process Analytics 26 Feb 2018

Research reveals anti-cancer effects of natural extract from Daffodils

A research describes the anti-cancer effects of a natural alkaloid extracted from Daffodils. Led by Denis Lafontaine, affiliated with the Faculty of Sciences at the ULB, the researchers have discovered that this compound triggers the activation of an anti-tumoral surveillance pathway.

26 Feb 2018

New discovery could help understand and treat glaucoma

Researchers have discovered two distinct groups of short molecules that regulate gene expression in the eyes of people with two different forms of glaucoma.

26 Feb 2018

Researchers develop first analytical method to evaluate new cyanide and mustard gas antidote

To develop antidotes for chemical agents, such as cyanide and mustard gas, scientists need analytical methods that track not only the level of exposure but also how the drug counteracts the effects of the chemical.

24 Feb 2018

Scientists reveal new insights into mechanism of gene regulation by 'magic spot'

Using an innovative crystallization technique for studying three-dimensional structures of gene transcription machinery, an international team of researchers, led by scientists at Penn State, has revealed new insights into the long debated action of the "magic spot"--a molecule that controls gene expression in Eschericahia coli and many other bacteria when the bacteria are stressed.

24 Feb 2018

Study unravels novel cellular and molecular pathway that regulates innate, adaptive immunity

Researchers at Brigham and Women's Hospital have discovered a new cellular and molecular pathway that regulates CD4+ T cell response--a finding that may lead to new ways to treat diseases that result from alterations in these cells.

24 Feb 2018

Researchers demonstrate novel process to produce cell-sized lipid vesicles

A team of researchers at the University of California in Irvine, California has demonstrated a novel process to produce cell-sized lipid vesicles (CLVs) from microfluidically generated double emulsion templates by investigating the interfacial parameters that control double emulsion stability for storage, and their subsequent dewetting to form multisomes or GUVs (subsets of CLVs).

24 Feb 2018

New low-cost microfluidic device brings single-cell technology to bedside

Single-cell analysis holds enormous potential to study how individual cells influence disease and respond to treatment, but the lack of cost-effective and user-friendly instrumentation remains challenging.

23 Feb 2018

Researchers discover mechanism that could open doors to new treatments for celiac disease

Celiac disease is an autoimmune disorder that affects by some estimates nearly 1 in 100 people. Celiac disease symptoms are triggered by gluten, a protein found in wheat and related plants, but gluten doesn't act alone to cause the digestive symptoms that patients suffer.

23 Feb 2018

UC Riverside researchers discover way to halt cancer metastasis

A research team at the University of California, Riverside has discovered a way for chemotherapy drug paclitaxel to target migrating, or circulating, cancer cells, which are responsible for the development of tumor metastases.

23 Feb 2018

Desymmetrization paves way for new bioactive compounds

Many chemical molecules can exist in nature together with their mirror counterparts; like hands, two compounds can be made up of the same atoms in the same overall structure but in opposite orientations, i.e. left-handed and right-handed.

23 Feb 2018

Stiffness of cancer cell plasma membrane affects uptake of nanomedicines

Nanomedicines need to get taken up by diseased cells in order to release their cargo. Cancer cells have altered membrane properties, which hamper their ability to take up nanomedicines.

23 Feb 2018

New staining method helps analyze 3D tissue samples using Nano-CT system

To date, examining patient tissue samples has meant cutting them into thin slices for histological analysis. This might now be set to change - thanks to a new staining method devised by an interdisciplinary team from the Technical University of Munich.

23 Feb 2018

Genetic variants make Asians and Europeans more prone to severe dengue

As globalization and climate change spread tropical infectious diseases around the globe, not all populations have the same degree of susceptibility.

23 Feb 2018

Researchers explore how evolutionary processes guide pathways of cells

Evolution describes how all living forms cope with challenges in their environment, as they struggle to persevere against formidable odds. Mutation and selective pressure--cornerstones of Darwin's theory--are the means by which organisms gain an advantageous foothold or pass into oblivion.

23 Feb 2018

Efficacy of cancer immunotherapy increased by deactivating tumor defence mechanism

Novel bifunctional immunotherapeutic agents have been developed that, as well as deactivating key immune checkpoints,deactivate the tumor's protective response.

23 Feb 2018

Sartorius’ second Research Xchange Forum spotlights regenerative medicine and cell therapy

Promoting interdisciplinary exchange between science and industry on the topics of regenerative medicine and cell therapy: this is the objective Sartorius will be pursuing by hosting its second Research Xchange Forum on March 20 and 21, 2018, at Sartorius College in Goettingen.

From Sartorius 23 Feb 2018

New study identifies mechanisms to lengthen egg viability in worms

Women have been told for years that if they don't have children before their mid-30s, they may not be able to. But a new study from Princeton University's Coleen Murphy has identified a drug that extends egg viability in worms, even when taken midway through the fertile window, which could theoretically extend women's fertility by three to six years.

23 Feb 2018

Researchers describe important step toward gene therapy for patients with Sandhoff disease

Babies with the rare, deadly genetic disorder Sandhoff disease begin to miss developmental milestones just months after birth. Lacking muscle tone, they never learn to sit up, develop heads too large to lift and eventually suffer uncontrollable seizures. There is no cure.

22 Feb 2018