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Polygenic risk score predicts early-onset heart disease risk

A risk score based on multiple genetic differences, or polygenic risk score, predicted significantly more cases of early-onset heart disease than standard tests for single genetic defects, according to new research in the American Heart Association's journal Circulation: Genomic and Precision Medicine.

8 Jan 2018

Bielefeld scientists discover cause of initially unclear symptoms

The sequencing of the human genome has made it possible: nowadays scientists can discover potential disorders for which there are no known patients.

5 Jan 2018

University of Montana researchers make discovery on unusual gene evolution in bacteria

University of Montana researchers have made another discovery at the cellular level to help understand the basic processes of all life on our planet - this time within the unusual bacteria that has lived inside cicada insects since dinosaurs roamed Earth.

5 Jan 2018

Newly described super-silenced DNA reveals novel approach to reprogram cells

Newly described stretches of super-silenced DNA reveal a fresh approach to reprogram cell identity to use in regenerative medicine studies and one day in the clinic, according to a study in Molecular Cell last week by investigators from the Perelman School of Medicine at the University of Pennsylvania.

5 Jan 2018

Genetic differences can influence efficiency of medicines

Medicines do not follow the one size fits all principle, because genetic differences can influence their efficiency.

5 Jan 2018

Cellular mechanism protects genes from damaging effects of mutation

Researchers at the University of Oxford have discovered that a cellular mechanism preferentially protects plant genes from the damaging effects of mutation.

5 Jan 2018

Precision editing of gut bacteria reduces inflammation in mouse model of colitis

UT Southwestern Medical Center researchers have used precision editing of the bacterial populations in the gut to prevent or reduce the severity of inflammation in a mouse model of colitis.

5 Jan 2018

Researchers use genomic technologies to better understand risk factor for stomach cancer

A research team led by National University Health System and Duke-NUS Medical School has used genomic technologies to better understand intestinal metaplasia, a known risk factor for gastric (stomach) cancer.

5 Jan 2018

Study suggests vitamin C enhances tuberculosis drugs effectiveness

A new study conducted by researchers at the Albert Einstein College of Medicine, Bronx, NY, proposed the use of vitamin C together with tuberculosis drugs for rapid eradication of the disease-causing pathogens. The studies were carried out on mice and in tissue cultures and the results have been published in the journal of American Society for Microbiology, Antimicrobial Agents and Chemotherapy.

5 Jan 2018

Study finds link between dietary sugar and increasing bacterial epidemics

The rising frequency and severity of Clostridium difficile infections may be caused by the commonly used food additive, trehalose, according to Nature.

5 Jan 2018

Why Should We Weigh Every Protein in the Human Body?

Our mission is to advance the measurement of human proteins with greater precision, to bring to the world the benefits of absolute molecular specificity when it comes to interrogating proteins at the molecular level.

From Pittcon 5 Jan 2018

Study provides insight into how early-stage breast cancer progresses to invasive ductal carcinoma

A new genetic-based model may explain how a common form of early-stage breast cancer known as ductal carcinoma in situ progresses to a more invasive form of cancer say researchers at The University of Texas MD Anderson Cancer Center.

4 Jan 2018

Researchers discover promising drug that shrinks excess fat without lowering food intake

Given the ever-increasing obesity epidemic, researchers from The University of Texas Medical Branch at Galveston have discovered a promising developing drug that has been shown to selectively shrink excess fat by increasing fat cell metabolism.

4 Jan 2018

Newly solved glucagon receptor structure provides most accurate template for drug design

Class B G protein-coupled receptors (GPCRs) exert essential action in hormonal homeostasis and are important therapeutic targets for a variety of diseases including metabolic disorders such as type 2 diabetes.

4 Jan 2018

Researchers optimize method to increase resolution of proteomic analysis

One of the key challenges of proteomics, the study of all proteins expressed by a cell or organism, is managing to distinguish between molecules that are structurally different yet have the same mass.

4 Jan 2018

Study illustrates the role of alcohol in causing damage to DNA and increased cancer risk

A new study conducted by a group of researchers at MRC Laboratory of Molecular Biology, Cambridge revealed the significant role of alcohol in causing damage to DNA in stem cells and thereby increasing cancer risks. The study was funded by Cancer Research UK and the results were published in Nature.

4 Jan 2018