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Multiple Sclerosis in Children

Multiple sclerosis (MS) is occasionally diagnosed in children and teens, though it occurs more often in adults. According to the latest estimates, around 9000 children in the United States have MS, and some studies report that 2-5% of MS patients start experiencing symptoms before age 18.

11 Aug 2016

Multiple Sclerosis and Pregnancy

Multiple sclerosis (MS) is often diagnosed in women of childbearing age, and this fact prompts concerns regarding how MS can affect pregnancy. Fortunately, several studies have demonstrated that women with MS experience similar issues (if any) with pregnancy, labor, delivery, and fetal complications as women without MS.

10 Aug 2016

Early Signs of Multiple Sclerosis

Multiple sclerosis (MS) is characterized by a variety of symptoms including impaired vision and numbness.

10 Aug 2016

Multiple System Atrophy Research

Multiple system atrophy (MSA) is a serious neurodegenerative disease with no available disease-altering therapies and no cure. Its natural history covers a 6 to 9 year course, during which the disease progresses to end in certain death. Currently available symptomatic therapies offer some relief, but more options are needed. Any change in outlook for patients with MSA will come from research.

10 Aug 2016

Signs and Symptoms of Multiple System Atrophy

Multiple system atrophy (MSA) is a neurodegenerative disease that affects involuntary body functions such as blood pressure and heart rate as well as movement. It is similar to Parkinson's disease, with onset around 50 years of age and a rapidly advancing course of disease over 5 to 10 years. In the late stages, pneumonia and sudden death are common. MSA affects about 15,000 to 50,000 people in the US.

10 Aug 2016

How is Multiple System Atrophy Diagnosed?

The diagnosis of MSA can be challenging because its initial symptoms resemble those of other diseases.

10 Aug 2016

Causes of Multiple System Atrophy

The fundamental cause of multiple system atrophy (MSA) is a loss of oligodendroglial and neuronal cells in the brain and central nervous system. The loss of cells is gradual and progressive, leading to slowly worsening symptoms.

10 Aug 2016

Multiple System Atrophy Treatment

People with multiple system atrophy (MSA) generally have a very poor prognosis. Their median survival is 6.2 to 9.5 years after the first symptoms appear. Patients who are older at the time of onset tend to have a shorter survival time. There are no therapies that cure or alter the disease or slow its progress, but there are many treatments available which may alleviate the symptoms of MSA.

10 Aug 2016

Multiple System Atrophy (MSA)

10 Aug 2016

Types of Multiple Sclerosis (MS)

Multiple sclerosis (MS) is a neurological disease affecting millions of people worldwide. It is a condition affecting the central nervous system (CNS) which comprises the brain and the spinal cord. In this condition, the immune system of the body attacks myelin, the protective sheath covering nerve fibers in the CNS. This leads to communication issues between the brain and the body and eventually results in irreversible damage to the nerves.

9 Aug 2016

Benign Multiple Sclerosis (MS)

Benign multiple sclerosis (MS) is a mild course of MS seen in 5-10% of MS patients. In people affected by benign MS, there is no worsening of functional ability even after 15 years of diagnosis. Currently, there is no way of predicting this form of MS at the time of diagnosis.

9 Aug 2016

Secondary Progressive Multiple Sclerosis (SPMS)

Secondary progressive multiple sclerosis (SPMS) is a form of MS that typically follows relapsing-remitting MS (RRMS). It is characterized by steady accumulation of disability without relapses.

9 Aug 2016

Relapsing-Remitting Multiple Sclerosis (RRMS)

Relapsing-remitting multiple sclerosis (RRMS) is found in about 85% of people diagnosed with MS and is the most common disease course.

9 Aug 2016

Primary Progressive Multiple Sclerosis (PPMS)

Primary progressive multiple sclerosis (PPMS) is an uncommon form of MS that affects approximately 10-15% of MS patients. In PPMS, symptoms steadily get worse over time without frequent relapses or remission.

9 Aug 2016

Phases of Chronic Myeloid Leukemia

Chronic myeloid leukemia (CML) is a type of cancer that begins in the cells in the bone marrow that are involved in the production of blood cells. The condition can be classified into 3 main phases according to specific characteristics, which helps to guide treatment decisions.

9 Aug 2016

Chronic Myeloid Leukemia Pathophysiology

The pathophysiology of chronic myeloid leukemia (CML) is important to understand so that we can tailor treatments to the specific characteristic of the disease. This helps to improve treatment outcomes and minimize general side effects of therapy, as targeted treatments for the condition can be introduced.

9 Aug 2016

Chronic Myeloid Leukemia Treatment

There are several other treatment methods that may be used to manage symptoms and prevent progression of chronic myeloid leukemia (CML), such as tyrosine kinase inhibitors, myelosuppressive therapy, splenectomy, and interferon alfa-2b treatment. It can also be cured with a bone marrow or allogeneic stem cell transplant.

9 Aug 2016

What Causes Goodpasture Syndrome?

Goodpasture syndrome is an autoimmune disorder which involves destruction of the glomerular and pulmonary alveolar basement membrane. The glomeruli are part of the filtering apparatus of the nephrons - the tiny units of the kidney. These are coiled loops of capillaries which filter out water and solutes from the blood passing through them. When the basement membrane is damaged by the autoantibodies formed in Goodpasture syndrome, glomerular cell proliferation occurs in response to cell-mediated immune responses, leading to the acute loss of renal function.

9 Aug 2016

Goodpasture Syndrome Treatment

Goodpasture syndrome requires early and effective treatment if it is not to be fatal. The regimens in use have decreased the mortality rate from the original 96% to less than 20%.

9 Aug 2016