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Social Security tackles overpayment ‘injustices,’ but problems remain

In March, newly installed Social Security chief Martin O'Malley criticized agency "injustices" that "shock our shared sense of equity and good conscience as Americans."

18 Nov 2024

Phase 2 study evaluates safety and efficacy of asunercept in COVID-19 patients

The ASUNCTIS trial evaluated asunercept's safety and efficacy in COVID-19, showing trends toward faster recovery despite not meeting statistical significance.

18 Nov 2024

Monash researchers develop model to tackle weight stigma in pregnancy and beyond

People with larger bodies commonly face a pervasive, resilient form of social stigma, often facing discrimination in the workplace as well as in educational and healthcare settings.

18 Nov 2024

Diabetes rates skyrocket globally with millions left untreated

The total number of adults living with either type 1 or type 2 diabetes in the world has surpassed 800 million - over four times the total number in 1990, according to findings from a global analysis published ahead of World Diabetes Day in The Lancet.

18 Nov 2024

Can music therapy be the breakthrough dementia care desperately needs?

Music therapy reduces distress and improves well-being in advanced dementia by meeting unmet needs, enhancing caregiver-patient understanding, and fostering humanizing connections in institutional care settings.

18 Nov 2024

New clinical trial offers hope for patients with rare immune disease IgG4-RD

A team led by Mass General Brigham researchers demonstrated that inebilizumab reduced the risk of symptoms by 87% in patients with the rare affliction known as immunoglobulin G4–related disease (IgG4-RD)

18 Nov 2024

CARMAT's Aeson device gains momentum in Europe as a bridge-to-transplant solution

CARMAT (FR0010907956, ALCAR), designer and developer of the world’s most advanced total artificial heart, aiming to provide a therapeutic alternative for people suffering from advanced biventricular heart failure (the “CARMAT”), provides an update on Aeson® artificial heart’s uptake as a bridge to transplant in Europe.

18 Nov 2024

Spermidine regulates RIPK1 to combat diabetes and vascular damage

Researchers reveal that spermidine-mediated acetylhypusination of RIPK1 suppresses necroptosis and insulin resistance, offering potential therapeutic strategies for type 2 diabetes.

18 Nov 2024

Neoantigen DNA vaccines improve survival and immunity in triple-negative breast cancer patients

A new phase 1 trial demonstrates the safety and effectiveness of personalized neoantigen DNA vaccines, showing promising immune responses and improved recurrence-free survival in high-risk triple-negative breast cancer patients.

17 Nov 2024

Engineered SNIPRs transform CAR T-cell precision for safer cancer therapy

Researchers developed SNIPRs, innovative receptors that sense soluble ligands, enabling precise therapeutic control in CAR T-cells. This breakthrough enhances tumor targeting while reducing off-target effects, paving the way for advanced synthetic biology applications.

17 Nov 2024

Growth hormone-releasing hormone transforms therapeutic potential in health and chronic disease

Researchers review the biological activities of growth hormone-releasing hormone and its analogs.

17 Nov 2024

Engineered virus-like particles evolve for superior gene delivery efficiency

Researchers developed a barcoded directed evolution system for engineered virus-like particles (eVLPs), creating a fifth-generation (v5) eVLP with enhanced production, transduction, and gene-editing efficiency. This system could pave the way for improved gene delivery vehicles in therapeutic applications.

17 Nov 2024

Are you falling for fake news? Age and analytical thinking might save you

Older adults and analytical thinkers excel at discerning true from false news, while ideological biases and political identity shape misinformation susceptibility in distinct ways.

17 Nov 2024

Zinc deficiency linked to increased risk of lung infection

Dietary zinc deficiency promotes lung infection by Acinetobacter baumannii bacteria -; a leading cause of ventilator-associated pneumonia, according to a new study published Nov. 15 in the journal Nature Microbiology.

15 Nov 2024

Pulses of light show promise in controlling seizures

In what could one day become a new treatment for epilepsy, researchers at UC San Francisco, UC Santa Cruz and UC Berkeley have used pulses of light to prevent seizure-like activity in neurons.

15 Nov 2024

Antiseizure medications during pregnancy linked to neurodevelopmental risks in children

Children born to mothers who take antiseizure medications to manage seizures and psychiatric conditions during pregnancy may face increased risks of neurodevelopmental conditions, according to new data from researchers at Drexel's Dornsife School of Public Health.

15 Nov 2024