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Strategic participant selection boosts reliability in brain imaging studies

Brain-wide association studies, which use magnetic resonance imaging to identify relationships between brain structure or function and human behavior or health, have faced criticism for producing results that often cannot be replicated by other researchers.

27 Nov 2024

SONIA trial demonstrates cost-effective treatment approach for advanced breast cancer

On November 27, the prestigious journal Nature will publish the results of an innovative breast cancer research project from the Netherlands.

27 Nov 2024

Understanding the pathophysiological relationship between OSA and metabolic syndrome

Cardiovascular diseases remain a leading cause of mortality globally, particularly among individuals with both obstructive sleep apnea (OSA) and metabolic syndrome (MetS).

27 Nov 2024

Adults with egg white allergy face significant quality of life challenges

Study reveals significant impairments in the quality of life for adults with hen's egg white allergy, highlighting the need for accurate food labeling and further research into effective treatments.

27 Nov 2024

Childhood social disadvantage linked to increased MS severity

People who develop multiple sclerosis (MS) as children and grow up in less advantaged neighborhoods may have a larger volume of inflammation and brain tissue loss on imaging than those who grow up in more advantaged neighborhoods, according to a study published in the November 27, 2024, online issue of Neurology, the medical journal of the American Academy of Neurology.

27 Nov 2024

Novel mRNA-based therapy offers hope for patients with proliferative vitreoretinopathy

A new preclinical study by Mass Eye and Ear investigators showed that a novel mRNA-based therapy may be able to prevent blindness and scarring from proliferative vitreoretinopathy (PVR) following a retinal detachment repair or traumatic injury to the eye.

27 Nov 2024

Stanford team uses natural cell death mechanism to kill cancer cells

Our bodies divest themselves of 60 billion cells every day through a natural process of cell culling and turnover called apoptosis.

27 Nov 2024

DNA-based nanorobotic hand could block viruses and enable rapid diagnostics

A tiny, four-fingered "hand" folded from a single piece of DNA can pick up the virus that causes COVID-19 for highly sensitive rapid detection and can even block viral particles from entering cells to infect them, University of Illinois Urbana-Champaign researchers report.

27 Nov 2024

HPV vaccine linked to significant decline in cervical cancer mortality

Cervical cancer deaths have plunged dramatically among women under age 25, and researchers at MUSC Hollings Cancer Center believe this is likely due to HPV vaccination.

27 Nov 2024

Study reveals protein mobility defect as a key factor in chronic diseases

Chronic diseases like type 2 diabetes and inflammatory disorders have a huge impact on humanity. They are a leading cause of disease burden and deaths around the globe, are physically and economically taxing, and the number of people with such diseases is growing.

27 Nov 2024

TRiC mutations found to cause developmental brain malformations in children

In 1992, Judith Frydman, PhD, discovered a molecular complex with an essential purpose in all of our cells: folding proteins correctly.

27 Nov 2024

Fungus found in the mouse stomach may hold a key to fungal evolution in the gut

A fungus discovered in the mouse stomach may hold a key to fungal evolution within the gastrointestinal tract, according to new research led by Weill Cornell Medicine investigators.

27 Nov 2024

Research shows "Alzheimer's in a dish" model can accelerate drug discovery

A decade ago, researchers introduced a new model for studying Alzheimer's disease. Known as "Alzheimer's in a dish," the model uses cultures of mature brain cells suspended in a gel to recapitulate what takes place in the human brain over 10 to 13 years in just six weeks.

27 Nov 2024

Younger age at type 2 diabetes diagnosis increases mortality risk

Research found that younger age at type 2 diabetes diagnosis is associated with higher risks of cardiovascular and all-cause mortality, emphasizing the need for early prevention and personalized management strategies.

27 Nov 2024

Culturally appropriate interventions strengthen healthcare responses to domestic violence

Culturally appropriate women-centred interventions can help healthcare systems respond to domestic violence, research has found.

27 Nov 2024

Can fasting improve diabetes outcomes? Ramadan offers insights

A study during Ramadan shows intermittent fasting improves liver health, gut microbiota richness, and metabolic markers in T2DM patients. However, benefits fade quickly after fasting ends, highlighting the need for sustained interventions.

27 Nov 2024

Philadelphia beverage tax: Did it curb childhood obesity?

The 2017 Philadelphia beverage tax aimed to reduce sugar-sweetened beverage consumption and improve pediatric health. While it significantly reduced sugary drink purchases, its impact on overall pediatric weight was limited, with minor changes observed in specific subgroups.

27 Nov 2024