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Trial compares the use of blood thinners after stenting in patients with acute coronary syndromes

Noninferiority was not demonstrated for death and ischemic events between P2Y12 inhibitor monotherapy and dual antiplatelet therapy (DAPT) given for 12 months after stenting in patients with acute coronary syndromes (ACS), according to late-breaking research presented in a Hot Line session today at ESC Congress 2025 and simultaneously published in New England Journal of Medicine.

3 Sep 2025

Impaired spatial orientation found in older adults at risk for Alzheimer’s disease

Individuals with an increased risk for dementia due to Alzheimer's disease can have impaired spatial orientation skills.

3 Sep 2025

Loneliness linked to higher NHS healthcare costs and poorer health in the UK

Lonely people incur an extra £850 in annual healthcare costs to the NHS, as well as experiencing worse mental and physical health

3 Sep 2025

Dual antiplatelet therapy shows no benefit over aspirin after CABG in patients with acute coronary syndrome

Dual antiplatelet therapy (DAPT) was not more effective than aspirin alone for the prevention of major adverse cardiovascular events and increased major bleeding in patients with acute coronary syndrome (ACS) who underwent coronary artery bypass grafting (CABG), according to late-breaking research presented in a Hot Line session today at ESC Congress 20251 and simultaneously published in New England Journal of Medicine.

3 Sep 2025

Stopping oral anticoagulation reduces risk after successful atrial fibrillation ablation

Discontinuing oral anticoagulation (OAC) therapy resulted in a lower risk of a composite of stroke, systemic embolism or major bleeding than continuing OAC therapy in patients who had successful ablation for atrial fibrillation at least 12 months previously, according to results from a late-breaking trial presented in a Hot Line session today at ESC Congress 2025 and simultaneously published in The Journal of the American Medical Association.

3 Sep 2025

Reconditioned pacemakers show comparable infection rates to new devices

Procedure-related infection rates were similar with reconditioned and new pacemakers, according to late-breaking research presented in a Hot Line session today at ESC Congress 2025.

3 Sep 2025

Sacubitril/valsartan shows benefit over enalapril in heart failure caused by Chagas disease

In patients with heart failure (HF) caused by Chagas disease, sacubitril/valsartan was superior to enalapril for the composite primary endpoint, predominantly driven by a significant reduction in N-terminal pro-B-type natriuretic peptide (NT-proBNP), according to late-breaking research presented in a Hot Line session today at ESC Congress 2025.

3 Sep 2025

Evolocumab fails to reduce vein graft disease after coronary artery bypass surgery

After coronary artery bypass grafting (CABG), evolocumab did not reduce saphenous vein graft disease rates at 2 years compared with placebo, according to late-breaking research presented in a Hot Line session today at ESC Congress 2025 and simultaneously published in Lancet.

3 Sep 2025

No clear benefit from surgical left atrial appendage occlusion in non-AF patients after valve surgery

No benefit in terms of prevention of ischemic stroke, transient ischemic attack and cardiovascular mortality after 1 year was observed when surgical left atrial appendage occlusion was performed in high-risk non-atrial fibrillation patients after valvular surgery, according to late-breaking research presented in a Hot Line session today at ESC Congress 2025.

3 Sep 2025

Study finds sex differences in schizophrenia and bipolar disorder

Schizophrenia and bipolar disorder are serious mental illnesses that affect both males and females, but research in Acta Psychiatrica Scandinavica indicates that sex may influence the characteristics and course of these conditions.

3 Sep 2025

Genetic variant disrupts brain’s cleanup crew increasing Alzheimer’s risk

A Nature study published today and led by researchers at the University of South Florida's USF Health Byrd Alzheimer's Institute pinpoints how a genetic variant disrupts microglia - the brain's "cleanup crew" - increasing the risk of Alzheimer's disease.

3 Sep 2025

New protein-based therapeutic tool could change the way we treat diseases

A team of scientists at Kyoto University's Institute for Integrated Cell-Material Sciences (iCeMS) has created a protein-based therapeutic tool that could change the way we treat diseases caused by harmful or unnecessary cells.

3 Sep 2025

Dental care gaps affect children with sickle cell disease in Michigan

Children with sickle cell disease are more likely to have dental problems - but fewer than half of those covered by Michigan Medicaid got dental care in 2022, according to a new study.

3 Sep 2025

Long-term benzodiazepine use linked to poor sleep quality in older adults

Long-term use of benzodiazepine and related drugs has been linked to poorer quality sleep in older adults with insomnia.

3 Sep 2025

Sugar-coated nanoparticles offer new hope for treating triple-negative breast cancer

Triple-negative breast cancer is particularly aggressive and difficult to treat; but recent research may offer a new way to target the often-deadly disease.

3 Sep 2025

Novel vascularized cancer-on-a-chip model reflects the microenvironment of liver tumors

Dr. Vadim Jucaud's lab at the Terasaki Institute has developed a human vascularized liver cancer-on-a-chip model to evaluate vessel remodeling and cell death in response to embolic agents.

3 Sep 2025

First complete brain activity map reveals how decisions are made

The first complete activity map of the brain has been unveiled by a large international collaboration of neuroscientists.

3 Sep 2025

Flooding from Hurricane Sandy raises heart disease risk years later

Although the material damage from 2012's Hurricane Sandy may have been repaired, the storm left a lasting impact on cardiovascular health, according to new findings from Weill Cornell Medicine and New York University researchers.

3 Sep 2025

Researchers uncover a promising new therapeutic target for Barth syndrome

Researchers at The Hospital for Sick Children (SickKids) have uncovered a promising new therapeutic target for Barth syndrome, a rare genetic condition with no current cure.

3 Sep 2025

Chronic stress and fatty diet disrupt brain-liver circuit leading to diabetes

This study discovered a circuit in the brain that connects stress with increased glucose and therefore may link stress to type 2 diabetes. In stressful situations, this circuit from the amygdala to the liver naturally provides a burst of energy.

3 Sep 2025

Medical News

Trial compares the use of blood thinners after stenting in patients with acute coronary syndromes

Impaired spatial orientation found in older adults at risk for Alzheimer’s disease

Loneliness linked to higher NHS healthcare costs and poorer health in the UK

Dual antiplatelet therapy shows no benefit over aspirin after CABG in patients with acute coronary syndrome

Stopping oral anticoagulation reduces risk after successful atrial fibrillation ablation

Reconditioned pacemakers show comparable infection rates to new devices

Sacubitril/valsartan shows benefit over enalapril in heart failure caused by Chagas disease

Evolocumab fails to reduce vein graft disease after coronary artery bypass surgery

No clear benefit from surgical left atrial appendage occlusion in non-AF patients after valve surgery

Study finds sex differences in schizophrenia and bipolar disorder

Genetic variant disrupts brain’s cleanup crew increasing Alzheimer’s risk

New protein-based therapeutic tool could change the way we treat diseases

Dental care gaps affect children with sickle cell disease in Michigan

Long-term benzodiazepine use linked to poor sleep quality in older adults

Sugar-coated nanoparticles offer new hope for treating triple-negative breast cancer

Novel vascularized cancer-on-a-chip model reflects the microenvironment of liver tumors

First complete brain activity map reveals how decisions are made

Flooding from Hurricane Sandy raises heart disease risk years later

Researchers uncover a promising new therapeutic target for Barth syndrome

Chronic stress and fatty diet disrupt brain-liver circuit leading to diabetes

Redefining control and consistency in anaerobic microbiome workflows

AI in Healthcare: How generative tools are transforming clinical practice

The future of automation: Machine learning–driven hepatocyte and organoid counting

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