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Japan's registry transforms outcomes for infants with biliary atresia

Biliary atresia (BA) is the leading cause of liver failure in infants, marked by progressive destruction of the bile ducts. Until the late 1950s, the disease was universally fatal, with no effective treatments. The development of the Kasai portoenterostomy brought new hope, but outcomes varied widely, and many patients still required liver transplantation (LTx).

8 Oct 2025

X-HiDE project advances toward earlier detection and precision treatment of inflammatory diseases

Facilitating earlier diagnosis and more precise treatment for patients with inflammatory diseases. This is the goal as the X-HiDE research project at örebro University in Sweden now enters its next phase, in collaboration with eleven companies and four other universities in Europe and the USA.

8 Oct 2025

Engineered Salmonella therapy delivers immune payloads to combat cancer

A new research paper was published in Volume 16 of Oncotarget on October 6, 2025, titled "ACTM-838, a novel systemically delivered bacterial immunotherapy that enriches in solid tumors and delivers IL-15/IL-15Rα and STING payloads to engage innate and adaptive immunity in the TME and enable a durable anti-tumor immune response."

8 Oct 2025

New dual-target vaccine shows promise against typhoid and Salmonella

Researchers at the University of Maryland School of Medicine's Center for Vaccine Development and Global Health (CVD) have completed a successful Phase 1 clinical trial of a novel vaccine designed to protect against both typhoid fever and invasive non-typhoidal Salmonella--two major causes of illness and death among children in sub-Saharan Africa.

8 Oct 2025

Engineered CAR-NK cells show enhanced cancer killing and immune evasion

One of the newest weapons that scientists have developed against cancer is a type of engineered immune cell known as CAR-NK (natural killer) cells. Similar to CAR-T cells, these cells can be programmed to attack cancer cells.

8 Oct 2025

Improved five-year cancer survival observed after Medicaid expansion

Adoption of Medicaid expansion in U.S. states appeared to improve both five-year cause-specific and overall survival in cancer patients.

8 Oct 2025

Asthma and multiple allergies raise the risk of failed oral food challenges

Research shows asthma and multi-food allergies elevate the odds of reactions in oral food challenges, emphasizing the importance of careful patient selection.

8 Oct 2025

California’s nursing shortage is getting worse. Front-line workers blame management.

California, like much of the nation, is not producing enough nurses working at bedsides to meet the needs of an aging and diverse population, fueling a workforce crunch that risks endangering quality patient care.

8 Oct 2025

This geriatrics training program escaped the Ax. for now.

In St. Louis, a team of students aboard a well-equipped van visits senior centers, a nursing home, a church, and other sites, learning to conduct comprehensive, hourlong geriatric assessments.

8 Oct 2025

Children burn energy and enjoy exercise with InPACT at Home program

InPACT at Home videos significantly boost children's physical activity energy expenditure, highlighting their role in promoting fitness and enjoyment at home.

8 Oct 2025

Empowering genomics research with cloud-based innovation

Discover how Discovery Life Sciences enhances genomics research with cloud-based platforms like DNAnexus.

From DNAnexus, Inc. 8 Oct 2025

Depression during pregnancy raises risk of gestational diabetes

Findings indicate that antenatal depression increases the risk of gestational diabetes, underscoring the need for early intervention and lifestyle support.

8 Oct 2025

Toxic e-waste pollution linked to rising childhood hypertension

The study reveals a fourfold increase in hypertension risk for children in e-waste regions, emphasizing the health impacts of toxic environmental pollutants.

8 Oct 2025

Non-standard baby formula linked to faster infant growth

The use of non-standard infant formulas is associated with higher growth rates in the first year, necessitating further research on long-term health effects.

8 Oct 2025

Aptamer expands into targeted radiopharmaceuticals with major top 3 pharma contract

Aptamer Group plc, the developer of next-generation synthetic binders for the life sciences industry, has announced a significant development contract with a top 3 global pharmaceutical company to engineer Optimer® binders as targeted radiopharmaceuticals for potential therapeutic applications.

8 Oct 2025

Healthy diet may double life expectancy benefits for frail adults

Research shows that improved diet quality significantly enhances life expectancy in frail older adults, highlighting the importance of nutrition in aging.

8 Oct 2025

Parental teasing and criticism fuel body image issues later in life

Verbal influences from parents on weight are key predictors of body image dissatisfaction in children, surpassing the effects of observed behaviors.

8 Oct 2025

Taste-based flu test that detects infection within minutes

Researchers examine the effectiveness of a novel taste-based sensor for the early detection of influenza infection.

8 Oct 2025

Calorie labeling in England linked to only small reductions in out-of-home food

Calorie labeling, which became law in April 2022 in England, is associated with only a small (2%) average reduction in the energy content of food that is available away from home, finds research published in the open access journal BMJ Public Health.

7 Oct 2025

UCSF and Allen Institute create most detailed data-driven map of the mouse brain

In a powerful fusion of AI and neuroscience, researchers at the University of California, San Francisco (UCSF) and Allen Institute designed an AI model that has created one of the most detailed maps of the mouse brain to date, featuring 1,300 regions/subregions.

7 Oct 2025