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Overcoming poor response to standard oral antiplatelet agents

Existing practice surrounding many cardiovascular medications, including anti-hypertensive and lipid-lowering agents, is based on the evaluation of response to therapy. In cases where ideal therapeutic targets (which have been identified through several previous studies) are not met in the single individual, there is evidence to support the need to intensify standard treatment so as to achieve better control of the cardiovascular risk factor under treatment (e.g. blood pressure or cholesterol levels) as this translates into a better outcome.

2 Sep 2008

Results from the Simvastatin and Ezetimibe in aortic stenosis study

The SEAS (Simvastatin and Ezetimibe in Aortic Stenosis) study has investigated the effects of intensive cholesterol lowering with the combination of simvastatin (40 mg daily) and ezetimibe (10 mg daily) in patients with aortic stenosis.

2 Sep 2008

Myocardial regeneration by intracoronary infusion in AMI (REGENT) randomized trial

REGENT is a multicenter, randomized trial for comparison of intracoronary infusion of bone marrow-derived unselected mononuclear cells (MNC) and selected CD34+CXCR4+ cells in 200 patients with acute myocardial infarction and reduced LVEF ¡Ü 40%.

2 Sep 2008

European guidelines for acute pulmonary embolism

Acute pulmonary embolism (PE) is a relatively common cardiovascular emergency. Clots originating in the leg veins may become detached and obstruct the lung vessels. This obstruction may lead to a rise of pressure in the pulmonary circulation and possibly to life-threatening heart failure.

2 Sep 2008

New guidelines on heart failure

Heart failure is a leading cause of death and hospitalisation and represents a major burden on health services. It is estimated that over 15 million people in Europe suffer from heart failure and the syndrome accounts for over 2% of national expenditure on health. The new guidelines on heart failure from the European Society of Cardiology are eagerly awaited.

2 Sep 2008

Older fathers more likely to have children with bipolar disorder

According to new research by Swedish scientists, older fathers are more likely to have children with bipolar disorder.

2 Sep 2008

Exercise on a treadmill helps stroke survivors years later

New research has found that exercising on a treadmill helped stroke survivors improve their mobility and physical conditioning.

2 Sep 2008

A new knee or hip has a life of three years

Research from the UK has found that hip and knee replacements in general last for around three years.

2 Sep 2008

Researchers say heart bypass a better option than drug-eluting stents

Major clinical research has found that for many patients with clogged arteries, bypass surgery is a better option than drug-eluting stents.

2 Sep 2008

Stress of motherhood turning women to drink

According to a new poll in Britain the stress of motherhood is turning many women to drink and some are knocking back a bottle of wine most nights.

2 Sep 2008

Survey reveals confusion of pregnant women

A survey in Britain of mothers and pregnant women has revealed an astonishing level of confusion and perplexity about being pregnant.

2 Sep 2008

Coffee appears to protect women from cancer of the uterus

Japanese researchers have discovered a good reason for women to drink coffee - they say it protects them from cancer of the uterus.

2 Sep 2008

Most vaccine-allergic children can still be safely vaccinated

With close monitoring and a few standard precautions, nearly all children with known or suspected vaccine allergies can be safely immunized, according to a team of vaccine safety experts led by the Johns Hopkins Children's Center. Writing in the September issue of Pediatrics, the multicenter research team offers pediatricians a step-by-step tool for quickly identifying children with allergic reactions to vaccines, and a much-needed guide, they say, to safely immunize those who are allergic.

2 Sep 2008

MorphoSys announces publication of first MOR103 data

MorphoSys AG announced today the publication of a first data package for its most advanced proprietary drug development program MOR103, a fully human HuCAL antibody directed against GM-CSF, in the journal "Molecular Immunology".

2 Sep 2008

Earwax removal - new guidelines

The American Academy of Otolaryngology - Head and Neck Surgery Foundation (AAO-HNSF) will issue the first comprehensive clinical guidelines to help health care practitioners identify patients with cerumen (commonly referred to as earwax) impaction. The guidelines emphasize evidence-based management of cerumen impaction by clinicians, and inform patients of the purpose of ear wax in hearing health.

1 Sep 2008

Atomic bomb's effect results in adult-onset thyroid cancer

Radiation from the atomic bomb blasts in Hiroshima and Nagasaki, Japan, in 1945, likely rearranged chromosomes in some survivors who later developed papillary thyroid cancer as adults, according to Japanese researchers.

1 Sep 2008

Playing and watching sports improves language skills

Being an athlete or merely a fan improves language skills when it comes to discussing their sport because parts of the brain usually involved in playing sports are instead used to understand sport language, new research at the University of Chicago shows.

1 Sep 2008

Children of older fathers more likely to have bipolar disorder

Older age among fathers may be associated with an increased risk for bipolar disorder in their offspring, according to a report in the September issue of Archives of General Psychiatry.

1 Sep 2008

Heavy snoring a sign of early carotid atherosclerosis

A study in the Sept. 1 issue of the journal Sleep shows that objectively measured heavy snoring is an independent risk factor for early carotid atherosclerosis, which may progress to be associated with stroke.

1 Sep 2008

Neuroimaging links chronic insomnia to reversible cognitive deficits without changes in behavior

A neuroimaging study in the Sept. 1 issue of the journal Sleep is the first to find that cognitive processes related to verbal fluency are compromised in people with insomnia despite the absence of a behavioral deficit. These specific brain function alterations can be reversed, however, through non-pharmacological treatment with sleep therapy.

1 Sep 2008