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Researcher transplants stem cells to try to save patients' legs

A Northwestern University Feinberg School of Medicine researcher has launched the first U.S. trial in which a purified form of subjects' own adult stem cells was transplanted into their leg muscles with severely blocked arteries to try to grow new small blood vessels and restore circulation in their legs.

23 Jan 2008

New compounds for treating tuberculosis and malaria

University of Navarra PhD in chemistry researcher, Esther Vicente, has discovered new compounds active for treating tuberculosis and malaria.

23 Jan 2008

Aspirin and non-steroidal anti-inflammatory drugs reduce risk of colorectal cancer

The use of regular, long-term aspirin and non-steroidal anti-inflammatory drugs (NSAIDs) reduces the risk associated with colorectal cancer, according to a study published in Gastroenterology , the official journal of the American Gastroenterological Association (AGA) Institute.

23 Jan 2008

New way to boost the immune system

Queen's University immunologists have discovered how to manipulate the immune system to increase its power and protect the body from successive viral infections.

23 Jan 2008

New anticancer drugs may block HSP90-IP6K2 protein interaction involved in cell death

Johns Hopkins researchers have discovered a previously unsuspected mechanism of cell death that may afford a new way to find and develop stronger yet less-harmful anticancer drugs.

23 Jan 2008

Pharmacists believe drive-through windows contribute to delays, errors

Consumers who pick up their prescription medications at a pharmacy drive-through window might be jeopardizing their own safety in the name of convenience.

23 Jan 2008

Obese patients with diabetes appear more likely to achieve remission with gastric banding

Preliminary research indicates that obese patients with type 2 diabetes who had gastric banding surgery lost more weight and had a higher likelihood of diabetes remission compared to patients who used conventional methods for weight loss and diabetes control, according to a study in the January 23 issue of JAMA: The Journal of the American Medical Association.

23 Jan 2008

Ovarian cancer risk not affected by alcohol and smoking, but reduced by caffeine

A new study has found that cigarette smoking and alcohol consumption do not have an effect on ovarian cancer risk, while caffeine intake may lower the risk, particularly in women not using hormones.

23 Jan 2008

Brain molecule from endothelial cells may be a new target for treatment of multiple sclerosis

In the February issue of Nature Immunology, the team provides fresh answers concerning the role of novel adhesion molecules in the pathogenesis of MS, a chronic autoimmune disease of the nervous system that affects approximately 55,000 young adults in Canada.

23 Jan 2008

Low vitamin E levels associated with physical decline in elderly

Researchers at Yale School of Medicine have found that a low concentration of vitamin E in the blood is linked with physical decline in older persons.

23 Jan 2008

New method for measuring protein synthesis

In a major breakthrough for future research and drug development, a team of Los Angeles Biomedical Research Institute (LA BioMed) investigators developed a new, more reliable method for measuring protein synthesis and turnover, processes that are critical to understanding cellular functions.

23 Jan 2008

Johns Hopkins to participate in 1000 Genomes Project

Researchers at the McKusick-Nathans Institute of Genetic Medicine (IGM) at Johns Hopkins will join other national and international scientists in the 1000 Genomes Project, an ambitious effort that will involve sequencing the genomes of numerous people from around the world to create the most detailed and medically useful picture to date of human genetic variation.

23 Jan 2008

New air sensor system will help asthmatics

Researchers at the Georgia Tech Research Institute (GTRI) have developed a sensor system that continuously monitors the air around persons prone to asthma attacks.

23 Jan 2008

Infants with poor intestinal flora often develop eczema

In a healthy intestinal system there is a great variety of natural bacteria.

23 Jan 2008

Heart and stroke death rates steadily decline; risks still too high

In an appropriate prelude to American Heart Month, which is just ahead in February, new mortality data from the Centers for Disease Control and Prevention (CDC) shows that, since 1999, coronary heart disease and stroke age-adjusted death rates are down by 25.8 percent and 24.4 percent, respectively.

23 Jan 2008

Genetic switches could lower cost of producing drugs, proteins

Bacteria have evolved complex mechanisms called quorum sensing systems that provide for cell-to-cell communication, an adaptation that allows them to wait until their population grows large enough before mounting an attack on a host or competing for nutrients.

23 Jan 2008

Gene variations associated with effectiveness of blood pressure medications

Patients with hypertension and certain gene variations experienced varying results with some blood pressure medications, suggesting matching a patient's genotype with certain hypertension medications could result in more favorable outcomes, according to a study in the January 23 issue of JAMA: The Journal of the American Medical Association.

23 Jan 2008