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Pathogens use previously undescribed mechanism to sabotage host immune system

New research identifies a previously unknown enzymatic mechanism that subverts the early host immune response and promotes pathogenicity by manipulating a common signaling pathway in host cells.

10 Dec 2007

Chikungunya in La Reunion - new findings

Researchers have discovered the key to how a mysterious mosquito-borne viral outbreak swept over the Indian Ocean island of La Reunion in 2005 and 2006, infecting about 266,000 people and causing at least 260 deaths — the first fatalities to be reported in connection with the virus, known as chikungunya.

10 Dec 2007

Research findings link weight gain and diabetes to a variety of cancers

During this holiday season with its tempting bounty of edible delights, new research calls attention to the role of the expanding American waistline in health and medicine.

10 Dec 2007

New understanding of chronic myeloid leukemia

Oregon Health & Science University Cancer Institute researchers have opened a new window into the roots of chronic myeloid leukemia (CML).

10 Dec 2007

Study shows how mutations in the BRCA1 gene lead to breast cancer

An international team of researchers led by Columbia University Medical Center's Herbert Irving Comprehensive Cancer Center and Sweden's Lund University has, for the first time, revealed how mutations in the BRCA1 gene lead to breast cancer.

10 Dec 2007

Brain overgrowth in 1-year-olds linked to development of autism

Brain overgrowth in the latter part of an infant's first year may contribute to the onset of autistic characteristics, according to research presented today at the American College of Neuropsychopharmacology (ACNP) annual meeting.

10 Dec 2007

New radiotherapy system benefits high-risk patients

A new radiotherapy system that combines high-tech imaging with precision tumor-targeting capability is helping cancer specialists at Stony Brook University Medical Center treat patients.

10 Dec 2007

Improprieties revealed at California Stem Cell Institute

More apparent conflict of interest violations in applications for research grants in California's $6 billion stem cell program were revealed and the Foundation for Taxpayer and Consumer Rights (FTCR) called for all the tainted applications to be rejected.

10 Dec 2007

Neurons in the frontal lobe may be responsible for rational decision-making

You study the menu at a restaurant and decide to order the steak rather than the salmon. But when the waiter tells you about the lobster special, you decide lobster trumps steak. Without reconsidering the salmon, you place your order - all because of a trait called "transitivity."

10 Dec 2007

Boost for tick disease research

Roman Ganta, a professor of diagnostic medicine and pathobiology at Kansas State University, has been awarded a grant of $1,825,000 by the National Institutes of Health to figure out how to stop the tick-borne bacteria, Ehrlichia chaffeensis, from making animals and people sick.

10 Dec 2007

Multiple myeloma clinical trial shows distinct survival benefit with lower dose of steroids

Results of Eastern Cooperative Oncology Group Phase III clinical trial E4A03, for multiple myeloma, showing significantly better overall survival with lenalidomide plus low-dose dexamethasone therapy compared to lenalidomide plus high-dose dexamethasone, were reported today by S. Vincent Rajkumar, M.D. at the American Society of Hematology's annual meeting.

10 Dec 2007

Tuberculosis found in 500,000-year-old human

Although most scientists believe tuberculosis emerged only several thousand years ago, new research from The University of Texas at Austin reveals the most ancient evidence of the disease has been found in a 500,000-year-old human fossil from Turkey.

10 Dec 2007

Mechanism for regulation of growth and differentiation of adult muscle stem cells is revealed

During muscle regeneration, which is a natural response to injury and disease, environmental cues cause adult muscle stem cells (satellite cells) to shift from dormancy to actively building new muscle tissue.

10 Dec 2007

Effects of diet and physical activity on the possibility of developing lung cancer

By simply eating four or more servings of green salad a week and working in the garden once or twice a week, smokers and nonsmokers alike may be able to substantially reduce the risk of developing lung cancer, say researchers at The University of Texas M. D. Anderson Cancer Center.

10 Dec 2007

Male circumcision

Circumcision is one of the commonest surgical procedures performed on males. Opponents argue that infant circumcision can cause both physical and psychological harm, while recent evidence shows that circumcision is medically beneficial.

10 Dec 2007

More good Gleevec news

Gleevec, the targeted cancer pill that has saved more than 100,000 lives, now is saving more children with a dire leukemia, as well as preventing disease progression with long term use in adults with chronic myeloid leukemia.

10 Dec 2007

Fever may restore nerve cell communications in regions of the autistic brain

The behavior of children with autism may improve during a fever, according to a first-of-kind study, "Behaviors Associated With Fever in Children With Autism Spectrum Disorders," published Nov. 30 in Pediatrics.

10 Dec 2007

FDA to review potential anti-arrhythmic claims for Ranexa

CV Therapeutics, Inc. has announced that the U.S. Food and Drug Administration (FDA) has notified the Company that it will evaluate the approval of potential anti-arrhythmic claims for Ranexa (ranolazine extended-release tablets) as part of its ongoing review of the Company's supplemental new drug application (sNDA).

10 Dec 2007

Doctors failing to diagnose HIV early in UK Africans

Doctors are missing valuable opportunities to diagnose HIV in Africans living in the UK, with serious consequences for their long term health, according to research funded by the Wellcome Trust.

10 Dec 2007

Denial of care for HIV+ detainees 'unacceptable,' says AHF

On the heels of the Human Rights Watch report descrying the treatment of HIV-positive immigrant detainees, AIDS Healthcare Foundation (AHF) has criticized the U.S. Department of Homeland Security (DHS) for its callous disregard for the health and well-being of people living with HIV/AIDS in its care.

10 Dec 2007