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Variations in cyclin D1 gene increase susceptibility to malignant melanoma

People who carry a particular genetic variant are at significantly increased risk of developing malignant melanoma, new research shows.

15 Sep 2008

Parents of dying newborns need clearer explanation of options

Parent-doctor discussions about whether to maintain or withdraw life support from terminally ill or severely premature newborns are so plagued by miscommunication and misunderstanding that they might as well be in different languages, according to a small but potentially instructive new study from Johns Hopkins Children's Center reported in the September issue of Pediatrics.

15 Sep 2008

Sun-damaged skin does not improve with estrogen treatments

Treating the skin with estrogen can stimulate collagen production-which improves the appearance of the skin-in areas not typically exposed to the sun, according to new research from the University of Michigan Health System.

15 Sep 2008

Promising new treatment option for women with recurrent ovarian cancer

Combining the new drug trabectedin with pegylated liposomal doxorubicin provides clinical benefit to women with relapsed ovarian cancer, according to new results presented at the 33rd Congress of the European Society for Medical Oncology (ESMO) in Stockholm.

15 Sep 2008

Scientists identify ependymoma genes

Scientists at The University of Nottingham have isolated three important genes involved in the development of a type of childhood brain cancer. The breakthrough is revealed in a study published in the British Journal of Cancer.

15 Sep 2008

An 'HIV-test' equivalent for early detection of lung cancer

A team of researchers led by Fred Hutchinson Cancer Research Center reports online today in the Journal of Clinical Oncology the validation of a potential "HIV-test" equivalent for the early detection of lung cancer. The test, which relies on immune-system signals, much like an HIV test, can detect the presence of lung cancer a year prior to diagnosis, long before symptoms appear.

15 Sep 2008

Lung cancer in non-smokers is sixth biggest cancer killer

While lung cancer in smokers and former smokers is the biggest cancer killer by far, lung cancer in people who have never smoked is -- by itself -- the sixth biggest cancer killer in the United States.

15 Sep 2008

Vaccine against HER2-positive breast cancer offers complete protection in lab

Researchers at Wayne State University have tested a breast cancer vaccine they say completely eliminated HER2-positive tumors in mice - even cancers resistant to current anti-HER2 therapy - without any toxicity.

15 Sep 2008

Pathways to clinical goals speeds cancer therapy approval

Although cancer remains a leading cause of death in America, it can take up to 12 years to bring a new anti-cancer agent before the FDA and the success rate for approval is only five to 10 percent. That means many research hours and dollars are wasted chasing avenues that will not bring fruit.

15 Sep 2008

Newer atypical antipsychotic medications no better than older drug in treating child and adolescent schizophrenia

Two newer atypical antipsychotic medications were no more effective than an older conventional antipsychotic in treating child and adolescent schizophrenia and may lead to more metabolic side effects, according to a new study funded by the National Institutes of Health's National Institute of Mental Health (NIMH).

15 Sep 2008

Inherited one-hit gene mutation provides new opportunity for colon cancer prevention

More than 30 years ago, Alfred Knudson Jr., M.D., Ph.D., revolutionized the field of cancer genetics by showing that a person must lose both their paternal and maternal copies of a particular class of cancer-inhibiting genes, called tumor-suppressor genes, in order to develop cancer.

15 Sep 2008

Cancer Research UK launches campaign to protect children from tobacco

Through 'Out of Sight, Out of Mind', the charity is aiming to protect the next generation from this deadly addiction and is calling on people across the UK to sign up to a petition to support its aims. Research shows that the younger people start to smoke, the harder they find it to quit and to stay quit for good, a worrying statistic as over 80 per cent of smokers start before the age of 19.

15 Sep 2008

European disparities in access to cancer drugs

New research has highlighted stark disparities in access to the latest cancer drugs across European Union nations, according to data presented at the 33rd Congress of the European Society for Medical Oncology (ESMO) in Stockholm.

15 Sep 2008

Scientists identify kidney failure susceptibility gene

Scientists at Johns Hopkins schools of Public Health and Medicine have, for the first time, identified variants in the gene MYH9 that are associated with increased risk for non-diabetic end stage renal disease (ESRD,) which is the near-loss of kidney function leading to either dialysis of transplant. MYH9, located on the 22 chromosome, is the first gene identified for common forms of kidney disease.

15 Sep 2008

Woman dies after being scratched by a wild rat

As a rule leptospirosis victims experience severe headaches and flu-like symptoms but the severe form which is Weil's disease, causes jaundice and liver damage, and can be fatal - but it usually only affects 10% of leptospirosis victims.

15 Sep 2008

More prostate cancer but fewer deaths

A major study by researchers from the Cancer Council Australia has found that even though more men are being diagnosed with prostate cancer, fewer are dying from the disease.

15 Sep 2008

Experts say thousands at risk for heart disease go unchecked

Australian experts say thousands at risk for heart disease go unchecked and are not getting the drugs which protect them.

15 Sep 2008

Staph infection a possible suspect in some SIDS cases

Australian researchers believe that some cases of sudden infant death syndrome (SIDS) may be caused by the bacterial infection Staphylococcus aureus (S. aureus).

15 Sep 2008

Investigational drug shows promise in ovarian cancer

An investigational drug that combats ovarian cancer by inhibiting the formation of new blood vessels has shown promise in a phase II trial, according to a presentation at the 33rd Congress of the European Society for Medical Oncology (ESMO) in Stockholm.

15 Sep 2008

Cambodia's condom campaign faces legal, financial issues, health official says

Cambodia's so-called 100% Condom Use campaign is being threatened by legal and financial issues, and the country could experience a resurgence of the disease, a health official said on Wednesday, AFP/Google.com reports.

15 Sep 2008