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A systems biology map of iron metabolism

Scientists at the Wake Forest University School of Medicine, the University of Manchester in the United Kingdom, and the Virginia Bioinformatics Institute at Virginia Tech have taken the first steps toward constructing a systems biology map of iron metabolism.

30 Apr 2009

DNA protecting protein helps cancer drug to kill cells

Some DNA repair enzymes can become double-edged swords - If they work too slowly, they can block necessary cell maintenance and contribute to cell death.

30 Apr 2009

Researchers identify a molecular target for quinoline compounds

The full details about the molecules and mechanisms that underlie the development of autoimmune diseases, such as multiple sclerosis and systemic lupus erythematosus, remain to be discovered.

30 Apr 2009

A universal vaccine to protect against pandemic influenza a step closer

An influenza vaccine that protects against death and serious complications from different strains of flu is a little closer to reality, Saint Louis University vaccine researchers have found.

30 Apr 2009

Scientists determine key structural features of mimivirus

The mimivirus is the largest virus known to scientists, about half of a micrometre (0.0005 millimeter) in diameter.

30 Apr 2009

Imiquimod, a topical cream, may help treat skin cancer

In a case study of a type of melanoma skin cancer typically found on chronically sun-exposed skin, Saint Louis University researchers found that imiquimod, a topical cream, produced good results for patients when used together with surgery to treat the cancer, potentially helping doctors cut less.

30 Apr 2009

Out-of-pocket costs reduce patients' willingness to start treatment for their chronic illnesses

Patients newly diagnosed with hypertension, diabetes or high cholesterol are significantly more likely to delay initiating recommended drug treatment if they face higher co-payments for medications, according to a new RAND Corporation study.

30 Apr 2009

Study suggests left-side bias in visual expertise

Facial recognition is not as automatic as it may seem. Researchers have identified specific areas in the brain devoted solely to picking out faces among other objects we encounter.

30 Apr 2009

Study examines radiation dose estimates for pregnant women undergoing therapeutic ERCP

Pregnant women with gallstone disease may require immediate endoscopic intervention because of potentially life-threatening cholangitis (infection in the bile ducts) or gallstone pancreatitis (inflammation of the pancreas).

30 Apr 2009

Smoking, hypertension and BMI are the leading preventable risk factors for premature mortality in the U.S.

The researchers found that smoking is responsible for 467,000 premature deaths each year, high blood pressure for 395,000, and being overweight for 216,000. The effects of smoking work out to be about one in five deaths in American adults, while high blood pressure is responsible for one in six deaths.

30 Apr 2009

Statins can lower PSA levels in men with prostate cancer

Beyond lowering cholesterol, statin medications have been found to have numerous other health benefits, including lowering a healthy man's risk of developing advanced prostate cancer, as well as lowering his prostate-specific antigen (PSA) levels.

30 Apr 2009

Stem cell focus for inflammatory bowel disease wound healing

Scientists at The University of Nottingham are investigating whether stem cell markers could have a role to play in speeding up wound healing in patients suffering from inflammatory bowel disease (IBD).

30 Apr 2009

Simple blood test proves powerful ally in the fight against malaria

Scientists at the Swedish medical university Karolinska Institutet have shown that rapid diagnostic tests (RDT) for malaria infection can provide valuable support for healthcare in low and mid-income countries in the fight against the disease.

30 Apr 2009

Study first to show an effective pre-pandemic vaccine approach

New research from the University of Leicester and University Hospitals of Leicester NHS Trust warns of a six-month time lag before effective vaccines can be manufactured in the event of a pandemic flu outbreak.

30 Apr 2009

Genes that influence brain cell connections linked to autism

In three studies, including the most comprehensive study of autism genetics to date, investigators funded in part by the National Institutes of Health have identified common and rare genetic factors that affect the risk of autism spectrum disorders.

30 Apr 2009

Regional anesthesia superior to general anesthesia for C-sections

General anesthesia (GA) is associated with an increased risk of infant intubation and low Apgar scores, relative to regional anesthesia.

30 Apr 2009

New initiative to ensure the safe use of methadone

The U.S. Substance Abuse and Mental Health Services Administration (SAMHSA) and the U.S. Food and Drug Administration (FDA) has launched an initiative to help ensure the safe use of methadone.

30 Apr 2009

Protein effects of hormone replacement therapy uncovered

An in-depth proteomic analysis of the sera of 50 participants from the Women's Health Initiative (WHI) hormone replacement therapy trial provides some explanations for the trial's clinical results.

30 Apr 2009