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A new method for breast cancer biomarker discovery

Three researchers from the Virginia Bioinformatics Institute (VBI) at Virginia Tech have developed and evaluated a new one-step bioanalytical approach that allows them to profile in detail complex cellular extracts of proteins. The method has allowed the scientists to look at how the levels of proteins change in breast cancer cells when they are treated with hormones or cancer drugs like tamoxifen.

9 Jun 2009

Researchers estimate risk of transmission of Huntington's disease to offspring among male carriers

Researchers from Boston University School of Medicine (BUSM) have quantified the probability of a male who carries a "high normal" variant of the Huntington's Disease (HD) gene having a child who develops the disease. Although thought to be a very rare event, the probability has never been estimated using current information and disease guidelines. The findings, appear on-line in the American Journal of Medical Genetics, may be useful during prenatal genetic counseling.

9 Jun 2009

Discovery of new angiogenesis protein - possible cancer drug target

To grow and spread, tumors need new blood vessels, a process called angiogenesis. One growth factor that causes angiogenesis has been identified - vascular endothelial growth factor or VEGF - and drugs to inhibit VEGF are already in use. But not all tumors respond to the therapy initially or over the long term. Thus new growth factors need to be identified to aid in developing the next generation of angiogenesis inhibitors.

9 Jun 2009

Novel approach for treating cognitive impairments

Researchers have been seeking a safe and effective way to treat cognitive impairments associated with schizophrenia by enhancing N-methyl-D-aspartate (NMDA) glutamate receptors. Functional deficits in NMDA receptors may contribute to the underlying neurobiology of this disorder.

9 Jun 2009

Colorectal cancer increasing globally

A new study finds colorectal cancer incidence rates for both males and females increased in 27 of 51 countries worldwide between 1983 and 2002, and points to increasing Westernization as being a likely culprit.

9 Jun 2009

Study reveals mechanism that could combat congenital limb defects like Holt-Oram syndrome

Gregg Duester, Ph.D., professor of developmental biology at Burnham Institute for Medical Research (Burnham), along with Xianling Zhao, Ph.D., and colleagues, have clarified the role that retinoic acid plays in limb development.

9 Jun 2009

Stopping type 1 diabetes damage with vitamin C

Researchers at the Harold Hamm Oklahoma Diabetes Center have found a way to stop the damage caused by Type 1 diabetes with the combination of insulin and a common vitamin found in most medicine cabinets.

9 Jun 2009

Antiretroviral therapy earlier yields better clinical outcomes

A clinical trial has demonstrated that HIV-infected adults in a resource-limited setting are more likely to survive if they start antiretroviral therapy (ART) before their immune systems are severely compromised.

9 Jun 2009

Gene variation associated with resistance to chemotherapy drug in women with breast cancer

Researchers have found links between an individual's genetics and their response to treatment with chemotherapy. The findings, by researchers at the National Cancer Institute (NCI), part of the National Institutes of Health, and colleagues, show how a genetic variant, located in the SOD2 gene, may affect how a person responds to the chemotherapy drug cyclophosphamide. Cyclophosphamide is used in the treatment of breast and other cancers.

9 Jun 2009

Dioxins in food chain linked to breastfeeding problems

Exposure to dioxins during pregnancy harms the cells in rapidly-changing breast tissue, which may explain why some women have trouble breastfeeding or don’t produce enough milk, according to a University of Rochester Medical Center study.

9 Jun 2009

Novel diabetes treatment Syncria (albiglutide) improves glucose control and reduces weight

New Phase II data presented today at the American Diabetes Association 69th Scientific Sessions in New Orleans show that the investigational type 2 diabetes treatment Syncria (albiglutide) significantly reduced blood glucose levels and provided weight loss across weekly, biweekly and monthly dosing. Reducing blood sugar is a key part of managing type 2 diabetes, a disease that affects over 250 million people worldwide.

9 Jun 2009

Sinovac begins production of H1N1 vaccine

Sinovac Biotech Ltd. announced today that it begins the production of a vaccine against influenza A (H1N1) virus. The virus seed was received from U.S. CDC and was delivered to the company on June 8, 2009.

9 Jun 2009

EU unions send message to ministers on healthcare

"We cannot let market forces run healthcare systems or we will end up with a two-tier system of healthcare delivery."

9 Jun 2009

Study redefines alcohol and smoking’s role in pancreatitis

Although alcohol consumption is known to be associated with chronic pancreatitis, new evidence indicates that a threshold of five or more drinks per day is required to significantly raise risk; however, most patients with chronic pancreatitis do not drink this amount, according to a report in the June 8 issue of Archives of Internal Medicine. In addition, smoking is an independent, dose-dependent risk factor.

9 Jun 2009

Expansion of Australia’s bowel cancer screening program could save 30 lives each week

New research has revealed that as many as 5 million Australians are missing out on bowel cancer screening tests that could save their lives and according to new data on bowel cancer screening released last week there is an urgent for all Australians over 50 to be screened.

9 Jun 2009

Australia's swine flu alert level may be raised a notch

As Australia's number of confirmed cases of influenza A H1N1 (swine flu) continues to soar - the toll is now 1,211 - there is now the very real possibility that the swine flu alert level will be raised a notch.

9 Jun 2009

Obesity and junk food the culprits in increased bowel cancer rates in young adults

New research by scientists in the United States has found despite the overall declining rates of colorectal cancer among adults younger than age 50 years the rates are increasing.

9 Jun 2009

The effect of computer game play on sleepiness and sleep hygiene

Computer/console gamers who play for more than seven hours a week and who identify their gaming as an addiction sleep less during the weekdays and experience greater sleepiness than casual or non-gamers, according to research presented at SLEEP 2009, the 23rd Annual Meeting of the Associated Professional Sleep Societies.

9 Jun 2009

Too much and too little sleep both linked to increased diabetes risk

According to a research abstract presented at SLEEP 2009, the 23rd Annual Meeting of the Associated Professional Sleep Societies, both long and short sleepers are at greater risk for diabetes. Individuals sleeping for more than eight hours per night may be particularly vulnerable.

9 Jun 2009

BMI may not provide an accurate picture of a person's health

Being overweight is a health concern, and using only body mass index (BMI) to determine weight classification may not give an accurate picture of a person's health, according to an advisory published in Circulation: Journal of the American Heart Association.

9 Jun 2009

Medical News

A new method for breast cancer biomarker discovery

Researchers estimate risk of transmission of Huntington's disease to offspring among male carriers

Discovery of new angiogenesis protein - possible cancer drug target

Novel approach for treating cognitive impairments

Colorectal cancer increasing globally

Study reveals mechanism that could combat congenital limb defects like Holt-Oram syndrome

Stopping type 1 diabetes damage with vitamin C

Antiretroviral therapy earlier yields better clinical outcomes

Gene variation associated with resistance to chemotherapy drug in women with breast cancer

Dioxins in food chain linked to breastfeeding problems

Novel diabetes treatment Syncria (albiglutide) improves glucose control and reduces weight

Sinovac begins production of H1N1 vaccine

EU unions send message to ministers on healthcare

Study redefines alcohol and smoking’s role in pancreatitis

Expansion of Australia’s bowel cancer screening program could save 30 lives each week

Australia's swine flu alert level may be raised a notch

Obesity and junk food the culprits in increased bowel cancer rates in young adults

The effect of computer game play on sleepiness and sleep hygiene

Too much and too little sleep both linked to increased diabetes risk

BMI may not provide an accurate picture of a person's health

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