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Knocking out Mcl1 protein could aid leukemia treatment

An effective way to fight leukemia might be to knock out a specific protein that protects cancer cells from dying, a new study shows.

21 Apr 2007

Significant genetic differences found in three types of chimpanzee

The largest study to date of genetic variation among chimpanzees has found that the traditional, geography-based sorting of chimps into three populations,western, central and eastern, is underpinned by significant genetic differences, two to three times greater than the variation between the most different human populations.

21 Apr 2007

Food-allergy management from the perspective of restaurant and food establishment personnel

A survey of restaurant and food establishment personnel reveals that for food-allergic consumers, dining out may be a greater risk than they realize.

21 Apr 2007

Gall bladder removed vaginally using endoscope

Medical and surgical endoscopists at NewYork-Presbyterian Hospital/Columbia University Medical Center removed a woman's gall bladder using a flexible endoscope with only minimal external incisions.

21 Apr 2007

Dental X-rays of carotid artery not enough to estimate stroke risk

Detection of calcified tissue in the carotid artery by dental x-rays is not enough evidence to estimate a patient's stroke risk was the conclusion of a systematic literature review published in this month's Journal of the American Dental Association (JADA).

21 Apr 2007

Stress-induced physiological changes in young teens

Adolescents who are chronically exposed to family turmoil, violence, noise, poor housing or other chronic risk factors show more stress-induced physiological strain on their organs and tissues than other young people.

21 Apr 2007

Taming chronic cough

Chronic cough – often causing much discomfort, frustration, irritability and sleep disturbances in 10 percent to 20 percent of adults – is one of the leading reasons for consultation with a physician according to a report published this month in Annals of Allergy, Asthma & Immunology , the scientific journal of the American College of Allergy, Asthma and Immunology (ACAAI).

21 Apr 2007

Discovery of molecular mechanism that alters strength of higher brain network connections

Yale School of Medicine and University of Crete School of Medicine researchers report in Cell April 20 the first evidence of a molecular mechanism that dynamically alters the strength of higher brain network connections.

21 Apr 2007

Aspirin use linked to moderate drop in cancer risk

A new American Cancer Society study finds men and women who used adult-strength aspirin (325 mg or more) daily for five or more years had an approximately 15 percent lower rate of developing any cancer than those who did not use aspirin.

20 Apr 2007

Women who take hormone replacement therapy are more likely to be diagnosed with ovarian cancer

Results from the Million Women Study, which is the biggest study of its kind in the world, show that over five years there is one extra case of ovarian cancer in every 2,500 women who take HRT. And for every 3,300 women who take HRT, there will be one additional death from ovarian cancer.

20 Apr 2007

ZARS announces Swedish marketing approval for Rapydan

ZARS, Inc. has announced that the Medical Products Agency in Sweden has approved Rapydan 70 mg/70 mg medicated plaster, a topical local anesthetic patch.

20 Apr 2007

Potential new test for breast cancer patients for abnormal reactions to radiotherapy

Medical scientists at the University of Leicester have announced a potentially unique advance in breast cancer research by identifying two genes associated with adverse reaction to cancer treatment.

20 Apr 2007

Why cisplatin kills breast cancer cells when other drugs fail

The cancerous cells of some individuals with breast cancer lack expression of two cell surface proteins, the estrogen and progesterone receptors, and do not express increased amounts of HER2.

20 Apr 2007

Protein called CREB key to memory storage in brain

Scientists know little about how the brain assigns cells to participate in encoding and storing memories.

20 Apr 2007

Lawmakers urged to provide much needed oversight of bioidentical hormones

Testifying before the United States Senate Special Committee on Aging, Dr. Leonard Wartofsky, president of The Endocrine Society strongly urged lawmakers to increase regulatory oversight of so-called "bioidentical hormones," which have been inaccurately promoted as a safer and more effective alternative to traditional hormone therapies for women.

20 Apr 2007

Treating berries with alcohol leads to an increase in antioxidant capacity

Strawberries are good for you, but serving them in daiquiri form may make them even healthier, scientists show.

20 Apr 2007

Smoking associated with worse outcomes in patients with prostate cancer treated by radical radiotherapy

A history of smoking is associated with an increased risk of metastatic disease in patients treated with radiotherapy (XRT) for prostate cancer (CaP), according to a report in the online version of the BJU International.

20 Apr 2007

Schering-Plough announces ZETIA spproved in Japan

Schering-Plough Corporation has announced that Schering-Plough K.K., the company's country operation in Japan, has received marketing approval for ZETIA (ezetimibe), a novel cholesterol-lowering agent that inhibits the absorption of cholesterol in the intestine.

20 Apr 2007

Risk and outcome similar for bypass surgery, drug-eluting stents

Drug-eluting stent therapy and bypass surgery for coronary artery disease have about the same risk for a major cardiac event within 30 days after the procedures, researchers reported at the American Heart Association's 8th Annual Conference on Arteriosclerosis, Thrombosis and Vascular Biology.

20 Apr 2007

Schering-Plough plans phase III trials for novel selective antiplatelet therapy

Schering-Plough Corporation has announced plans to initiate two global Phase III large-scale clinical outcomes trials for its novel selective oral antiplatelet therapy, the thrombin receptor antagonist (TRA) SCH 530348.

20 Apr 2007