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Disease modifying activity of 2ME2 demonstrated in preclinical rheumatoid arthritis studies

EntreMed a clinical-stage pharmaceutical company developing therapeutics primarily for the treatment of cancer and inflammatory diseases, has announced the presentation of positive preclinical results for its lead compound, 2-methoxyestradiol (2ME2), in models of rheumatoid arthritis.

24 Aug 2005

Scientists convert human embryonic stem cells into lung cells

According to research to be published in the journal Tissue Engineering, the team from Imperial College London, took human embryonic stem cells and 'directed' them to convert into the type of cells needed for gas exchange in the lung, known as mature small airway epithelium.

24 Aug 2005

Female college students do better overall

America's female college students study more, are more likely to read their textbooks thoroughly and to earn "A"s in their courses, and expect to graduate in less time than their male counterparts.

24 Aug 2005

Brain can be tricked into thinking the pain has gone

A new U.S. study has found that it is possible that by just thinking that a medicine will relieve pain is enough to prompt the brain to release its own natural painkillers, and soothe painful sensations.

24 Aug 2005

No intervention is necessary for most children with fluid in their ears

A Children's Hospital of Pittsburgh study finds that prompt insertion of tympanostomy tubes (small ear tubes) does not improve developmental outcomes of children at 6 years of age as once thought.

24 Aug 2005

FDA Approves Aceon to reduce risk of cardiovascular mortality in patients with stable coronary artery disease

Solvay Pharmaceuticals and CV Therapeutics have announced that the U.S. Food and Drug Administration (FDA) has approved Aceon (perindopril erbumine) Tablets for the treatment of patients with stable coronary artery disease to reduce the risk of cardiovascular mortality or non-fatal myocardial infarction (MI).

24 Aug 2005

China on high alert - new case of pig disease in Hong Kong

After the central government said this week that it had the pig disease under control in Sichuan province, the epicentre of the outbreak, China's far south is now on high alert after one person was killed and three were infected by the disease that has killed nearly 40 in the southwest.

24 Aug 2005

Mouse model of Rett Syndrome displays reduced cortical activity

Sacha Nelson of Brandeis University in Waltham, MA and Rudolf Jaenisch of the Whitehead Institute of Biomedical Research in Cambridge, MA and their colleagues report online in the Proceedings of the National Academy of Sciences Early Edition that spontaneous neuronal activity is reduced in the cortex of a knockout mouse model for the childhood neurodevelopmental disorder, Rett Syndrome.

23 Aug 2005

A preoperative testing strategy may help determine stage of lung cancer more accurately

A preoperative testing strategy combining two procedures may help improve the accuracy of determining the stage of lung cancer, according to an article in the August 24/31 issue of JAMA: The Journal of the American Medical Association.

23 Aug 2005

First direct evidence that endorphins play a role in the phenomenon known as the placebo effect

Just thinking that a medicine will relieve pain is enough to prompt the brain to release its own natural painkillers, and soothe painful sensations, a new University of Michigan study finds.

23 Aug 2005

Use of general anesthesia for heroin detoxification offers no benefit when compared to two other methods

The use of general anesthesia for heroin detoxification offers no benefit when compared to two other methods, and is associated with several potentially life-threatening adverse events, according to an article in the August 24/31 issue of JAMA: The Journal of the American Medical Association.

23 Aug 2005

No major difference in the incidence of dementia between men and women

A new study on the incidence of dementia in England and Wales, published in the forthcoming issue of the open access journal PLoS Medicine, challenges three commonly held assumptions about dementia.

23 Aug 2005

European Rare Diseases Therapeutic Initiative could provide an important new mechanism for developing new drugs

Because of the very high costs in developing drugs for rare genetic diseases, and the low return on investment, the pharmaceutical industry has rarely developed specific treatments for many of these diseases.

23 Aug 2005

Susceptibility to Hepatitis A in patients with chronic liver disease due to Hepatitis C virus infection: missed opportunities for vaccination

A new study examining whether patients with chronic Hepatitis C virus (HCV) were routinely vaccinated against Hepatitis A virus (HAV) found that vaccination rates were low, even though HAV vaccination is recommended for patients with chronic liver disease.

23 Aug 2005

New drug CX717 can temporarily improve performance and reverse the effects of sleep deprivation

Research in monkeys suggests that a new drug can temporarily improve performance and reverse the effects of sleep deprivation on the brain, which would be a breakthrough in helping shift workers, health professionals, military personnel and others who must function at top performance in spite of sleep deficits.

23 Aug 2005

Medical News

Disease modifying activity of 2ME2 demonstrated in preclinical rheumatoid arthritis studies

Scientists convert human embryonic stem cells into lung cells

Female college students do better overall

Brain can be tricked into thinking the pain has gone

No intervention is necessary for most children with fluid in their ears

FDA Approves Aceon to reduce risk of cardiovascular mortality in patients with stable coronary artery disease

China on high alert - new case of pig disease in Hong Kong

Mouse model of Rett Syndrome displays reduced cortical activity

A preoperative testing strategy may help determine stage of lung cancer more accurately

First direct evidence that endorphins play a role in the phenomenon known as the placebo effect

Use of general anesthesia for heroin detoxification offers no benefit when compared to two other methods

No major difference in the incidence of dementia between men and women

European Rare Diseases Therapeutic Initiative could provide an important new mechanism for developing new drugs

Susceptibility to Hepatitis A in patients with chronic liver disease due to Hepatitis C virus infection: missed opportunities for vaccination

New drug CX717 can temporarily improve performance and reverse the effects of sleep deprivation

Unique blood test detects iron deficiency in infants earlier

First study to test the role of RNA chemical modifications on immunity

Aspirin use can significantly reduce the risk of colorectal cancer

Benefits of MAO-B inhibitors are small but may be worthwhile in some patients with early Parkinson's disease

Coronavirus HCoV-NL63 associated with croup

How can microdialysis benefit drug development

Global and Local Efforts to Take Action Against Hepatitis

Addressing Important Cardiac Biology Questions with Shotgun Top-Down Proteomics

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