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NSAIDs okay for tonsillectomy, new study finds

When children have their tonsils removed, nonsteroidal anti-inflammatory drugs can be used for pain relief with no significant increase in bleeding and with less nausea and vomiting, according to a systematic review of current evidence.

19 Apr 2005

Combination chemotherapy shows small survival benefit in advanced stomach cancer

Patients with advanced stomach cancer have the best chance of prolonging their survival with a combination of chemotherapies instead of just one, according to a new review of previous studies.

19 Apr 2005

Some Alzheimer’s patients can benefit from drug Memantine

The drug memantine can reduce cognitive deterioration and loss of everyday functions in patients with moderate to severe Alzheimer’s disease, according to a new review of studies.

19 Apr 2005

Searching for the right pharmaceutical agent: survival as the indicator

Tumor cells divide fast. They thus require a high supply of components for their DNA, like purines. The biosynthesis of purines could now be a new point of attack for chemotherapy. However, without a natural model, the search for an inhibitor for a cellular process is like the proverbial search for a needle in a haystack. An American research team has developed a clever way to quickly conjure the desired "needle" out of the hay, presenting several candidates to act as starting points for the design of a purine synthesis inhibitor.

19 Apr 2005

Researchers identify marker of heart disease in low-birthweight babies

Some low birth weight infants have large particles rich in apolipoprotein C-1, a blood protein that could put them at risk for heart disease later in life, according to a national study led by Johns Hopkins Children's Center researchers.

19 Apr 2005

Number and quality of kidney transplants much greater if national matching program adopted

A collaboration between Johns Hopkins and Massachusetts Institute of Technology scientists has mathematically demonstrated that a national matching program for kidney paired donation, also called paired kidney exchange, would ensure the best possible kidney for the greatest number of recipients who have incompatible donors.

19 Apr 2005

Researchers find promising cancer-fighting power of synthetic cell-signaling molecule

Novel anti-cancer compounds called Enigmols suppress the growth of human cell lines representing cancers of the prostate, breast, colon, ovary, pancreas, brain and blood, and reduce tumors in three animal studies, new research shows.

19 Apr 2005

World's first recipient of insulin-producing cells from a living donor

A 27-year-old diabetic woman has become the world's first recipient of insulin-producing cells from a living donor.

19 Apr 2005

Concern about the environment grows in East Asia as impacts of pollution and urbanization increase

Pollution and environmental degradation increasingly threaten the health of East Asia and Pacific's rapidly urbanizing population, according to two new environment reports from the World Bank.

19 Apr 2005

If MyPyramid can assist people in effectively adopting the recommendations of the Dietary Guidelines, it will be a great success

The ultimate value and success of the new “MyPyramid” Food Guidance System graphic will be measured by whether it can serve as an effective tool to help people eat according to the 2005 Dietary Guidelines for Americans. Time will tell if MyPyramid will convey to consumers the vital nutritional messages of balance, variety, moderation and adequacy.

19 Apr 2005

New chemical reaction that could greatly accelerate pharmaceutical production

University of Toronto researchers have a developed a new chemical reaction that could greatly accelerate pharmaceutical production, while also cutting costs and toxic by-products.

19 Apr 2005

Obesity is straining America's knees

America's expanding waistline is straining its knees--and pocketbook--with hundreds of thousands of overweight people undergoing surgery every year because the extra pounds they pack are leading to tears in their meniscal cartilage.

19 Apr 2005

Ancient protein could be critical to stopping the uncontrolled division of tumor cells that cause cancer

Molecular Biology and Microbiology professor Mark Muller has found that the protein, called MKRN1, promotes the destruction of an enzyme called telomerase that enables rapid duplication of cells. While researchers have known for years that healthy cells repress telomerase, they haven't understood why.

19 Apr 2005

New method for the study of ion channel gating kinetics

An ion channel is a protein pore that lets ions (charged atoms such as calcium) pass through a cell's membrane. The method fits data to a new class of models, called manifest interconductance rank (MIR) models, which will give researchers a better understanding of the mechanisms by which ion channels open and close.

19 Apr 2005

Short segments of sugar chains useful in search for new drugs for Alzheimer's

Heparansulfate, which is needed for normal fetal development among other things, is also important for the build-up of amyloid, morbid protein deposits that appear in several serious diseases. This is shown by Uppsala scientists in an article published in the Proceedings of the National Academy of Science.

19 Apr 2005

Researchers insert engineered human stem cells into the spinal cords of ALS-afflicted rats

Unveiling a delivery method that may one day help surgeons treat the deadly neurodegenerative disease amyotrophic lateral sclerosis (ALS), researchers at the University of Wisconsin-Madison have inserted engineered human stem cells into the spinal cords of ALS-afflicted rats.

19 Apr 2005

Vegetables such as broccoli and spices like red chili pepper, may provide a cancer-fighting benefit

Two new studies suggest that vegetables such as broccoli and spices like red chili pepper, may provide a cancer-fighting benefit by slowing or preventing the growth of cancerous tumor cells. The findings, being presented at the annual meeting of the American Association for Cancer Research held April 16 to 20 at the Anaheim Convention Center in Anaheim, Calif., looked at the effect of these dietary agents on cancers that have extremely poor prognoses despite advances in surgery and other therapies.

19 Apr 2005

Protein studies may lead to new Alzheimer's test

A study appearing in an upcoming issue of the Journal of Alzheimer's Disease, published by IOS Press, entitled "Quantitative proteomics of cerebrospinal fluid from patients with Alzheimer disease," may lead to a new test for diagnosing the devastating illness. About 4 million Americans suffer from Alzheimer's disease, the most common form of dementia, characterized by memory loss and an inability to use language.

19 Apr 2005

Paramedics need family support services

Support services provided to paramedics should also be made available to their family members if these families are to remain healthy and intact, says a University of Toronto researcher.

19 Apr 2005

Marker of heart disease in low-birthweight babies identified

19 Apr 2005

Medical News

NSAIDs okay for tonsillectomy, new study finds

Combination chemotherapy shows small survival benefit in advanced stomach cancer

Some Alzheimer’s patients can benefit from drug Memantine

Searching for the right pharmaceutical agent: survival as the indicator

Researchers identify marker of heart disease in low-birthweight babies

Number and quality of kidney transplants much greater if national matching program adopted

Researchers find promising cancer-fighting power of synthetic cell-signaling molecule

World's first recipient of insulin-producing cells from a living donor

Concern about the environment grows in East Asia as impacts of pollution and urbanization increase

If MyPyramid can assist people in effectively adopting the recommendations of the Dietary Guidelines, it will be a great success

New chemical reaction that could greatly accelerate pharmaceutical production

Obesity is straining America's knees

Ancient protein could be critical to stopping the uncontrolled division of tumor cells that cause cancer

New method for the study of ion channel gating kinetics

Short segments of sugar chains useful in search for new drugs for Alzheimer's

Researchers insert engineered human stem cells into the spinal cords of ALS-afflicted rats

Vegetables such as broccoli and spices like red chili pepper, may provide a cancer-fighting benefit

Protein studies may lead to new Alzheimer's test

Paramedics need family support services

Marker of heart disease in low-birthweight babies identified

How can microdialysis benefit drug development

Global and Local Efforts to Take Action Against Hepatitis

Addressing Important Cardiac Biology Questions with Shotgun Top-Down Proteomics

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