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Why people get drowsy and fall asleep, and how caffeine blocks that process

When cells in a certain part of the brain become overworked, a compound in the brain kicks in, telling them to shut down. This causes people to become drowsy and fall asleep. Alter that natural process by adding coffee or tea, and the brain compound – called adenosine – is blocked, and people stay awake.

20 Apr 2005

Arthritis medications (methotrexate and leflunomide) commonly used in adults are safe and effective in children

An international team of researchers, led by Dr. Earl Silverman of The Hospital for Sick Children (Sick Kids), has found that two arthritis medications (methotrexate and leflunomide) commonly used in adults are safe and effective in children. This research is reported in the April 21, 2005 issue of The New England Journal of Medicine.

20 Apr 2005

Louder neurons drown out their quieter neighbors

As the brain develops, neurons reach out helter-skelter to form new connections, only a small number of which take hold. How the brain chooses which connections to keep and which to prune back appears to be governed by which branches have the most electrical activity-a finding that could help to explain how early experiences guide brain development.

20 Apr 2005

Antibiotic treatment does not reduce risk of secondary cardiac events

Taking antibiotics weekly for one year does not reduce the risk of a heart attack or other cardiac event for patients with stable coronary artery disease, according to a study funded by the National Heart, Lung, and Blood Institute of the National Institutes of Health. It is published in the April 21, 2005, edition of the New England Journal of Medicine.

20 Apr 2005

Discovery of brain's first known 'safety circuit' gives new perspective on anxiety disorders

Scientists at Columbia University Medical Center have made a surprising finding about positive emotions that should change the way people think about anxiety disorders.

20 Apr 2005

Insights could yield new approaches to nerve regeneration

Nervous system development requires billions of neurons to migrate to the appropriate locations in the brain and grow nerve fibers (axons) that connect to other nerve cells in an intricate network.

20 Apr 2005

Cigarette smoking may contribute to the progression of multiple sclerosis

Researchers from the Harvard School of Public Health (HSPH) recently discovered that cigarette smoking may contribute to the progression of multiple sclerosis (MS), suggesting that quitting smoking could limit or delay central nervous system deterioration.

20 Apr 2005

Gene that plays a key role in brain wiring

The complexity of the brain and, more specifically, how nerve cells form billions of contacts when there are fewer than 30,000 human genes is still a scientific mystery.

20 Apr 2005

Electroshock therapy speeds improvement in schizophrenia patients

Shock therapy, a controversial practice conjuring frightening images of behavior control, still has a place in schizophrenia treatment, a newly updated research review shows.

20 Apr 2005

ASTRO public awareness campaign wins award

The American Society for Therapeutic Radiology and Oncology’s public awareness campaign to educate cancer patients on their treatment options has won an Award of Distinction from The Communicator Awards in their 2005 Print Media competition. ASTRO also received Awards of Distinction for its quarterly magazine, ASTROnews, and its Annual Meeting Guide magazine supplement.

20 Apr 2005

First study of mercury and cognitive function in urban, U.S. adults

Although the omega-3 fatty acids found in fish are well known for their health benefits, many fish are also the primary source of mercury in the general population.

20 Apr 2005

Johns Hopkins ACG risk adjustment system to be used in Spain, Portugal

Researchers at the Johns Hopkins Bloomberg School of Public Health have signed a four-year agreement with Iasist of Barcelona, Spain, which will give Iasist distribution rights to the JHU Adjusted Clinical Groups® Case-Mix System (ACG System) in Spain and Portugal. Iasist is currently assisting the Basque National Health Service (Osakidetza) in using the ACG System to allocate resources among primary care clinics.

20 Apr 2005

Brain-injury rehabilitation depends on acetylcholine circuitry

The ability of the brain to recover from such injury as stroke or trauma depends on a particular circuitry of neurons that "talk" to one another using the brain chemical acetylcholine, researchers led by James Conner and Mark Tuszynski in the Neural repair Group at UCSD have discovered.

20 Apr 2005

Researchers find ovarian cancer patients who appear to respond better than others to gefitinib, or Iressa

Researchers at Fox Chase Cancer Center in Philadelphia have identified a subset of ovarian cancer patients who appear to respond better than others to gefitinib, or Iressa. The research was presented today at the 96th Annual Meeting of the American Association for Cancer Research in Anaheim, Calif.

20 Apr 2005

New drug, RAD001, shown to stop the growth of ovarian cancer cells

A new drug, RAD001, has been shown to stop the growth and movement of certain ovarian cancer cells, according to scientists at Fox Chase Cancer Center in Philadelphia. The research was presented today at the 96th Annual Meeting of the American Association for Cancer Research (AACR) in Anaheim, Calif.

20 Apr 2005

Football is the sport most likely to cause neck injury

According to new research published in the British Journal of Sports Medicine, football beats hockey and soccer for the dubious distinction of the sport most likely to cause neck injury.

20 Apr 2005

Enhancing the resources available to low-income, urban African American women could protect against poor health and symptoms of depression

Enhancing the resources available to low-income, urban African American women to make their neighborhoods safer could protect them against poor health and symptoms of depression, says Tulane University School of Public Health and Tropical Medicine community health researcher Adam Becker.

20 Apr 2005

New method for obtaining sequence information from thousands of genomes simultaneously

One of the world’s leading scientists, Nobel Prize winner, Dr Sydney Brenner, has devised a new method for obtaining sequence information from thousands of genomes simultaneously. Current technologies can only analyse one genome at a time.

20 Apr 2005

Men estimate men's risks of common disorders higher than women do, and vice versa

New research from University of Glasgow researchers on lay perceptions about gender differences in health reveals that both men and women believe health risks are higher for their own sex than for the opposite sex. But, it also shows that males think that men are fitter and females think women are more athletic.

20 Apr 2005