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Lilly launches publicly available clinical trial registry

Eli Lilly and Company today will announce the launch of its publicly available clinical trial registry, www.lillytrials.com, which will post the results from all Phase I through Phase IV clinical trials of Lilly's marketed products.

8 Dec 2004

Chiron flu vaccine banned for a further three months

The Chiron Corporation, a vaccine manufacturer, were told today that the suspension of their licence for manufacturing influenza vaccine at the Speke factory in Liverpool, would continue for a further three months.

8 Dec 2004

HHS purchases 1.2 million doses of GSK's Fluarix flu vaccine

HHS Secretary Tommy G. Thompson has announced that the Food and Drug Administration authorized the use of GlaxoSmithKline influenza vaccine, Fluarix, in the United States under an Investigational New Drug application.

8 Dec 2004

Leg wounds can be accurately assessed using photographs taken at a patient's home

A pilot study has shown that leg wounds can be accurately assessed using photographs taken at a patient's home, adding one more example to a growing list of medical conditions that can be successfully monitored remotely.

8 Dec 2004

Trimming fat overcomes one of the major obstacles to drug design

Biochemists at Ohio State University and their colleagues have overcome one of the major obstacles to drug design, by trimming some of the fat from a molecular sponge that scientists use to study proteins.

8 Dec 2004

Teen-agers suffering from bulimia may also be struggling with a chronic form of depression

Teen-agers suffering from bulimia may in fact be fighting a two-front war, coping with the effects of a devastating eating disorder while struggling with a chronic form of depression, reveals research by Texas A&M University psychologist Marisol Perez

8 Dec 2004

New research is allowing biochemists to understand a key hierarchy of protein interactions that occurs in DNA

"All cancers are marked by some form of DNA replication gone awry, so a basic understanding of DNA replication is of paramount importance to those designing cancer-fighting drugs,"

8 Dec 2004

Resveratrol antioxidant found in red wine may benefit heart tissue

New research on rat heart cells suggests that a well-known antioxidant found in red wine, called resveratrol, may benefit heart tissue by limiting the effects of a condition called cardiac fibrosis.

8 Dec 2004

Defect in one of nature's oldest proteins may be an underlying cause in human miscarriages

University of Rochester scientists studying a vital protein called Serum Response Factor (SRF) in mice have learned new and unexpected facts about SRF's role in early cardiovascular development, and how a defect in this gene may be an underlying cause in human miscarriages.

8 Dec 2004

Thiazolidinedione (TZD) class of anti-diabetic drugs may be a potential targeted therapy for myeloma patients

In laboratory tests on multiple myeloma cells, University of Rochester researchers found that this type of cancer expresses a protein that makes it an easy target for an existing class of diabetes drugs. After more investigation, they hope the discovery will lead to a new, targeted therapy for myeloma patients.

8 Dec 2004

Dermatologists recommend adding an E to the ABCD acronym for recognizing early melanomas

One more letter should be added to the alphabetic list of warning signs of melanoma, a potentially deadly skin cancer, according to a group of NYU School of Medicine dermatologists and their Australian colleagues.

8 Dec 2004

Neurobiologists distinguish in unprecedented detail the patterns of brain activity

Using hairlike microelectrodes and computer analysis, neurobiologists at Duke University Medical Center have demonstrated that they can see the detailed instant-to-instant electrical "brainscape" of neural activity across a living brain.

8 Dec 2004

Transplanted bone marrow cells reduce liver fibrosis in mice

Transplanted bone marrow cells can reduce carbon tetrachloride-induced liver fibrosis in mice and significantly improve their survival rates, according to a new study

8 Dec 2004

A new study has found fatty liver disease in nearly one third of American adults in a large urban population sample

The prevalence of the disease varied significantly among ethnic groups. Hispanics had a higher prevalence than whites, while blacks had a lower prevalence than whites.

8 Dec 2004

Patients and GPs agree on out of hours care

New research published today (Wednesday 8 December 2004) by DPP: Developing Patient Partnerships shows that high quality care and good access to health professionals are key concerns for both patients and GPs.

8 Dec 2004

Accumulated exposure to lead may be an important but unrecognized risk for developing cataracts in men

Lead continues to pose a significant public health problem in spite of substantial reductions in lead exposure in the United States in the recent past, according to background information in the article.

8 Dec 2004

Men and women who were overweight in young adulthood and middle age have significantly higher Medicare costs in older age

According to background information, obesity is associated with increased risk of high blood pressure, diabetes, and certain cancers, and has been identified as a major risk factor for coronary heart disease (CHD).

8 Dec 2004

Breast MRI moderately useful for detecting breast cancer

In women with breast lesions that are suspicious for cancer, based on clinical examination or mammography, performing a breast MRI has high sensitivity but only moderate specificity for detecting breast cancer, but does not necessarily eliminate the need for tissue sampling, according to a study in the December 8 issue of JAMA.

8 Dec 2004

DNA crystal that computes as it grows

In a demonstration that holds promise for future advances in nanotechnology, California Institute of Technology computer scientists have succeeded in building a DNA crystal that computes as it grows. As the computation proceeds, it creates a triangular fractal pattern in the DNA crystal.

7 Dec 2004

No need for mass burial of flood victims

The World Health Organization (WHO) has advised that the bodies of people who die in floods and other natural disasters do not normally pose a risk of infection and there is no need to dispose of them in mass graves.

7 Dec 2004

Medical News

Lilly launches publicly available clinical trial registry

Chiron flu vaccine banned for a further three months

HHS purchases 1.2 million doses of GSK's Fluarix flu vaccine

Leg wounds can be accurately assessed using photographs taken at a patient's home

Trimming fat overcomes one of the major obstacles to drug design

Teen-agers suffering from bulimia may also be struggling with a chronic form of depression

New research is allowing biochemists to understand a key hierarchy of protein interactions that occurs in DNA

Resveratrol antioxidant found in red wine may benefit heart tissue

Defect in one of nature's oldest proteins may be an underlying cause in human miscarriages

Thiazolidinedione (TZD) class of anti-diabetic drugs may be a potential targeted therapy for myeloma patients

Dermatologists recommend adding an E to the ABCD acronym for recognizing early melanomas

Neurobiologists distinguish in unprecedented detail the patterns of brain activity

Transplanted bone marrow cells reduce liver fibrosis in mice

A new study has found fatty liver disease in nearly one third of American adults in a large urban population sample

Patients and GPs agree on out of hours care

Accumulated exposure to lead may be an important but unrecognized risk for developing cataracts in men

Men and women who were overweight in young adulthood and middle age have significantly higher Medicare costs in older age

Breast MRI moderately useful for detecting breast cancer

DNA crystal that computes as it grows

No need for mass burial of flood victims

How can microdialysis benefit drug development

Global and Local Efforts to Take Action Against Hepatitis

Addressing Important Cardiac Biology Questions with Shotgun Top-Down Proteomics

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