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Morse code for human cells

Morse code is a simple, effective and clear method of communication and now scientists believe that cells in our body may also be using patterns of signals to switch genes on and off. The discovery may have major implications for the pharmaceutical industry as the signalling molecules that are targeted by drugs may have more than one purpose.

10 Jan 2005

Important clue to understanding the origins of the AIDS epidemic

Medical Research Council (MRC) scientists have uncovered an important clue to understanding the origins of the AIDS epidemic. The work suggests that harnessing natural mechanisms of resistance to HIV infection might provide new methods for combating AIDS.

10 Jan 2005

Scientists examine the role of small sputum macrophages in the widespread disease chronic obstructive bronchitis

COPD (chronic obstructive pulmonary disease) is one of the most common fatal diseases worldwide. In Germany alone, there are about 3-5 million patients affected. COPD includes both chronic obstructive bronchitis and emphysema. Both represent irreversible changes of the central and lower respiratory tract which are accompanied by coughing, mucus production and difficulty in breathing.

10 Jan 2005

Potential new therapies for cancer and bleeding disorders

Lexicon Genetics announced today that it has advanced two of its drug discovery programs into preclinical development in preparation for investigational new drug (IND) applications.

10 Jan 2005

Idiopathic pulmonary fibrosis study points to survival as key endpoint in future actimmune studies

InterMune, Inc. today announced that CHEST, the journal of the American College of Chest Physicians, published an important analysis of variables that measure clinical outcomes in patients with idiopathic pulmonary fibrosis (IPF), a deadly and debilitating lung disease.

10 Jan 2005

Rotary blood pump shows promise for pediatric patients

Ventricular assist devices (VADs), blood pumps used in heart failure situations, now have the potential for use in additional patient groups. Scientists and clinicians gathered at the 11th Congress of the International Society of Rotary Blood Pumps in Germany last year to discuss past lessons learned and future directions for this technology.

10 Jan 2005

Velcade (bortezomib) phase III clinical trial initiated in patients with newly diagnosed multiple myeloma

Millennium Pharmaceuticals today announced, in collaboration with Johnson & Johnson Pharmaceutical Research & Development, LLC, the initiation of VISTA (Velcadeas Initial Standard Therapy in multiple myeloma: Assessment with melphalan and prednisone), a multicenter, international phase III clinical trial of Velcadein combination with melphalan and prednisone versus melphalan and prednisone in patients with newly diagnosed multiple myeloma (MM) who are not transplant candidates.

10 Jan 2005

Ranbaxy files anti-retrovirals (ARVs) to the U.S. FDA

Ranbaxy Laboratories Limited (Ranbaxy) announced today that the Company has so far made three filings of its Anti-Retrovirals (ARVs) to the U.S. FDA for its approval under the expedited review process of the President's Emergency Plan for AIDS Relief (PEPFAR).

10 Jan 2005

How Elvis would have looked at 70

On the eve of what would have been the 70th birthday of Elvis Presley, scientists have created a computer-generated image of how the King would have looked today if he were still alive.

10 Jan 2005

Vital research into the effects of premature birth throughout childhood

Results of a follow-up study into babies born extremely prematurely was published last week (Thursday 6 January) in the New England Journal of Medicine.

10 Jan 2005

Scientists identify genes that promote the growth and recurrence of skin cancer

Andrzej Dlugosz, M.D., a professor of dermatology in the U-M Medical School, and colleagues at the University of Michigan and the National Cancer Institute examined the functions of the Hedgehog (Hh) signaling pathway in basal cell carcinoma – the most common form of cancer – and uncovered a subset of tumor cells that were resistant to inhibition of the Hedgehog pathway.

10 Jan 2005

Seven percent of college students have used prescription stimulants for non-medical purposes

Seven percent of college students have used prescription stimulants for non-medical purposes over their lifetimes and 4 percent have used in the past year, according to a study of students at 119 four-year colleges and universities nationwide published in the January issue of the journal Addiction.

10 Jan 2005

Scientists reveal how we recognise the look of fear

Whether it's the look of love, happiness, or the look of fear, humans use facial expressions to communicate important information to one another. But which parts of the brain read these cues, and how do they do it?

10 Jan 2005

Girls' diets call for more calcium

Mother Nature's best efforts to protect growing bones come up short when girls' diets contain too little calcium, according to a study at the USDA Children's Nutrition Research Center at Baylor College of Medicine in Houston.

10 Jan 2005

Serono announces the availability of Saizen for adult growth hormone deficiency

Serono announced today the availability of Saizen [somatropin (rDNA origin) for injection] for use in the treatment of patients with adult growth hormone deficiency (AGHD), following its FDA approval.

10 Jan 2005

High rate of disability in extremely premature babies, new research results reveal

The follow-up results of a major study into babies born extremely prematurely have revealed that a high number of these children have a disability, although the levels of severity vary widely.

10 Jan 2005

Scientists identify a protein that regulates alcohol-withdrawal seizures

Seizures are the most life-threatening, as well as disconcerting, symptoms of withdrawal in people who are alcoholics and who abruptly stop drinking. Heavy consumption of alcohol, or ethanol, the substance in beer, wine and liquor that is addictive, leads to changes in the brain.

10 Jan 2005

Body drumming a hit for phobics

Conquering a fear of heights or spiders might be as easy as some strategic body drumming.

10 Jan 2005

Groundbreaking study will assist stroke and head injury victims rehabilitate their sight

For the first time, Crawford and his associates used measurements of eye and head movements, computer simulations and brain recordings, to determine how we use vision to guide our movements.

10 Jan 2005

Key genetic factor determines HIV/AIDS risk

People with more copies of a gene that helps to fight HIV are less likely to become infected with the virus or to develop AIDS than those of the same geographical ancestry, such as European Americans, who have fewer copies of the gene, according to a study funded by the National Institute of Allergy and Infectious Diseases (NIAID).

10 Jan 2005