Applied Biosystems launches MeltDoctor High-Resolution Melt Reagents for scanning DNA

Applied Biosystems, part of Life Technologies Corporation (NASDAQ:LIFE), today announced the launch of genomic analysis tools that will help researchers in studies that associate genetic variation with specific diseases. These new tools, known as the MeltDoctor™ High-Resolution Melt (HRM) Reagents, are for research use only and are part of a PCR-based workflow that enables researchers to cost-effectively scan DNA from a variety of biological sample types to detect the smallest genetic variations among samples.

The MeltDoctor HRM Reagents facilitate high resolution melt, or HRM analysis, which is a powerful technique for the detection of mutations, polymorphisms and epigenetic differences in double-stranded DNA samples. These reagents enable the characterization of variant nucleic acid sequences for advanced genomics applications such as mutation scanning, genotyping, and methylation analysis. These tools, including software, are part of an HRM analysis workflow optimized for Applied Biosystems real-time PCR systems that is simple to perform, requiring minimal quantities of both sample and reagent to capture a significantly greater amount of detail and information for variant types, without the complexity and expense of other methods.

HRM analysis is emerging as a technique of choice among genomics researchers and is one of several different analysis methods offered by the Genomics Core Lab at the Institute of Research in Immunology and Cancer at the University of Montreal. The IRIC Genomics Core Facility has been using an early-access version of the MeltDoctor HRM Reagents to simplify SNP analyses and to characterize new variants in candidate genes for immunology and cancer research studies.

Comments

The opinions expressed here are the views of the writer and do not necessarily reflect the views and opinions of News Medical.
Post a new comment
Post

While we only use edited and approved content for Azthena answers, it may on occasions provide incorrect responses. Please confirm any data provided with the related suppliers or authors. We do not provide medical advice, if you search for medical information you must always consult a medical professional before acting on any information provided.

Your questions, but not your email details will be shared with OpenAI and retained for 30 days in accordance with their privacy principles.

Please do not ask questions that use sensitive or confidential information.

Read the full Terms & Conditions.

You might also like...
Persistent activation of DNA damage response in the liver after MASLD reversal