High-fructose corn syrup makes rats fat: Princeton University study questioned

Dr. Marion Nestle questions Princeton Study:

"HFCS makes rats fat? I can hardly believe that Princeton sent out a press release yesterday announcing the results of this rat study. The press release says: "Rats with access to high-fructose corn syrup gained significantly more weight than those with access to table sugar, even when their overall caloric intake was the same."

A March 22, 2010 press release entitled "A sweet problem: Princeton researchers find that high-fructose corn syrup prompts considerably more weight gain" issued by Princeton University was based on a study that used grossly exaggerated intake levels in rats and incorrectly suggested that such results could have significant meaning for humans.

In the study "High-fructose corn syrup causes characteristics of obesity in rats: Increased body weight, body fat and triglyceride levels," the authors failed to put into perspective the excessive amount consumed by the rats in their experimental design. Translating the study's reported rat intakes to human proportions, the calories gained from high fructose corn syrup would be equivalent to about 3000 kcal/day all from that single source. In comparison, adult humans consume about 2,000 calories per day from all dietary sources. Such intake levels for the study animals would be the equivalent of humans drinking a total of 20 cans of 12 ounce sodas per day - a highly unrealistic amount. Moreover, the researchers concluded that the rats gained more weight from high fructose corn syrup than they would have from sugar, yet the researchers had no proper basis for drawing this conclusion since they failed to provide sucrose controls for part of the study's short-term experiments and no sucrose controls whatsoever were present in any of the long-term experiments.

"Consumers should not be misled by exaggerated studies that feed astronomical amounts of one ingredient to the study subjects, in this case rats. The medical community has long dismissed results from rat dietary studies as being inapplicable to human beings," stated Audrae Erickson, president, Corn Refiners Association.

"Consumers should rest assured that high fructose corn syrup is safe. The American Medical Association concluded that high fructose corn syrup does not appear to contribute more to obesity than sugar. The American Dietetic Association stated that these two sweeteners are indistinguishable to the human body and are metabolized equivalently," Erickson noted.

"This study unnecessarily confuses consumers about human metabolism of common sugars in the diet. A sugar is a sugar whether it comes from cane, corn, or beets. Both sugar and high fructose corn syrup are handled the same by the body. No metabolic effects have been found in studies that compare sugar and high fructose corn syrup consumption in humans," concluded Erickson.

SOURCE Corn Refiners Association