Addition of ECC probe to SOLiD System's chemistry achieves greater than 99.99% single-read accuracy

Life Technologies Corporation (NASDAQ: LIFE), a provider of innovative life science solutions, today announced that it has established a new standard in accuracy for next generation sequencing. By adding an Exact Call Chemistry (ECC) proprietary probe to its market leading ligation chemistry, the company has demonstrated greater than 99.99% average single-read accuracy. This high-accuracy data is essential for the detection of minor variants in heterogeneous samples, a critical area of importance in cancer research. Further, the data is output in standard basepair format, allowing easier interface with third party tertiary data analysis tools.

“The unprecedented level of accuracy that we can now deliver with ECC makes the SOLiD™ System's chemistry ideal for deciphering the 'acquired' genetic code of cancer and achieving whole genome 'germline' sequencing at lower coverage and cost.”

"Looking for minor variants in a disease such as cancer can be like looking for a needle in a haystack," said Mark Stevenson, President and Chief Operating Officer of Life Technologies. "The unprecedented level of accuracy that we can now deliver with ECC makes the SOLiD™ System's chemistry ideal for deciphering the 'acquired' genetic code of cancer and achieving whole genome 'germline' sequencing at lower coverage and cost."

Life Technologies will present data supporting this groundbreaking achievement at its workshops at the upcoming meeting of the American Society of Human Genetics (ASHG). Scientists wishing to attend a special event can RSVP by visiting>