Cooked tomatoes could help in prostate cancer: Study

By Dr. Ananya Mandal, MDFeb 1 2012

New research shows that tomatoes could help cure prostate cancer.

Scientists have discovered the nutrient, lycopene, which is found in cooked tomatoes, can slow the growth and even kill the cancer cells. Dr Mridula Chopra and colleagues at the University of Portsmouth found that lycopene, which gives tomatoes their red color, intercepts the cancer's ability to make the connections it needs to attach to a healthy blood supply.

Lycopene is present in all red fruits and vegetables, but its concentrations are highest in tomatoes and it becomes more readily available and biologically active when it comes from processed tomatoes with a small amount of cooking oil added.

The researchers, from the university's School of Pharmacy and Biomedical Sciences, are now calling for tests to check if the same reaction occurs in the human body.

Dr Chopra said, “I stress that our tests were done in test tubes in a laboratory and more testing needs to be carried out to confirm our findings, but the laboratory evidence we have found is clear - it is possible to intercept the simple mechanism some cancer cells use to grow at concentrations that can be achieved by eating sufficient cooked tomatoes.” She added, “The type of tomatoes which offer the most effective lycopene also differs and more tests need to be done to find the best breed of tomato for this purpose.”

The research, which is published in the British Journal of Nutrition, was part-funded by Heinz. Heinz asked for further research to follow up earlier studies by the same researchers which showed a significant increase in lycopene levels in blood and semen samples after subjects ate 400g (14oz) of processed tomatoes for two weeks.

Eleanor Barrie, senior science information officer at Cancer Research UK, said, “Some existing cancer drugs target the formation of new blood vessels, but more research is needed to show how they could be used to help cancer patients…This small study doesn't directly tell us if lycopene has any effect against cancer, but research like this can help us to understand more about how the chemical affects blood vessel formation.”