Rexahn Pharmaceuticals, Inc. (NYSE Amex: RNN), a clinical stage pharmaceutical company developing and commercializing potential best in class oncology and CNS therapeutics, today announced the publication of a research article in Journal of Medicinal Chemistry [55: 4521-4525, 2012] on the anti-tumor activity of its RX-3117 compound.
The data demonstrates the synthesis of RX-3117 and its 2'-deoxy analogue, as well as its in vitro cell-line activity and strong in vivo anti-tumor effect.
"This study provides further evidence of RX-3117's potential as an anti-cancer compound," said Rick Soni, President of Rexahn. "In the preclinical study, RX-3117 significantly inhibited growth of human cancer cells in vitro and the growth of tumors in in vivo models of nude mice."