CARLINA, GenBiotech to jointly develop prolonged-release protein formulation for cartilage repair

Nov 5 2014

CARLINA Technologies, a biotechnology company specialized in the development of nanomedicines, today announces the signing of a collaborative agreement with GenBiotech for the development of a prolonged-release pharmaceutical form of a protein. The resultant protein will be used in bone and cartilage repair. Financial details were not disclosed.

The development of the product will utilize the patented technology platform PEPTIDOTs(TM) owned by CARLINA Technologies. PEPTIDOTS is a unique process allowing the encapsulation of therapeutic peptides and proteins without altering their structure, therefore maintaining their full biological activity.

CARLINA Technologies develops nanomedicines using proprietary controlled-delivery technologies applied to off-patent drugs. It has currently three product candidates under development, PEPTIDOTS–insulin and PEPTIDOTS-somatotropin, for improved treatments of diabetes and growth hormone deficiencies, and SOLUDOT-PTX, a tumor-targeted anticancer nanomedicine to treat companion animals with cancer. CARLINA also provides R&D services in formulation development with out-licensing opportunities to improve the efficacy and safety of proprietary drugs from the pharma & veterinary industries.

This agreement provides an option for GenBiotech to acquire exclusive worldwide rights on CARLINA Technologies’ platform PEPTIDOTS to develop, sub-license, or commercialize this product specifically for cartilage repair for animal health. The result of the collaboration for CARLINA Technologies will also serve as a proof-of-concept supporting the use of the PEPTIDOTS platform with a number of other therapeutic proteins, including antibodies, growth factors and interleukins. CARLINA Technologies will aim to collaborate with other pharmaceutical companies involved in protein-based therapeutics that could benefit from its technology platforms.

“Nanomedicines and their development programs are becoming critical to the pharmaceutical industry. CARLINA Technologies has been working with GenBiotech for a number of years and we are delighted that our collaboration will be expanded with a partnership agreement,” said Olivier Meyer, President & CEO of CARLINA Technologies. “This collaboration will contribute to the development of an important protein in the much needed bone cartilage repair area. It is also an additional demonstration of the potential of PEPTIDOTS, CARLINA’s technology platform.”