Moffitt researchers David Basanta, PhD, and Conor Lynch, PhD, have been awarded a U01 grant to investigate prostate cancer metastasis. Prostate cancer frequently spreads to the bone, and can cause painful bony lesion and increased mortality for patients. Their study will integrate molecular, cellular and clinical information into mathematical models to better understand key factors driving the disease to help target when metastasis may occur and identify new therapeutic targets for its prevention.