Bristol scientist develops novel ophthalmic device that could prevent vision loss worldwide

Jun 20 2017

Dr Shelby Temple, from the University of Bristol's School of Biological Sciences, has been named Innovator of the Year 2017 for his ground-breaking work into polarization and macular degeneration.

The Biotechnology and Biological Sciences Research Council (BBSRC) award recognizes Dr Temple's work in developing a device that can rapidly screen people at increased risk of age-related macular degeneration (AMD), the worldwide leading cause of incurable blindness in people over 55.

The innovation arose from BBSRC-funded research carried out at the University of Bristol, which looked at the ability of octopuses, cuttlefish and coral reef fish to see a polarized light - an aspect of light that humans aren't typically aware they can see. Dr. Temple invented a series of unique devices to display polarized light to animals, and in doing so, realized he could see a pattern as well.

"What I was seeing was an effect known as Haidinger's brushes, which happens within the eye when people perceive polarized light. The ability to see this phenomenon is linked to an aspect of eye health and can be an early indicator of disease.

"It became clear that the tools I had developed for octopuses and cuttlefish could be the foundation for a novel ophthalmic device that could rapidly screen people for susceptibility to AMD," said Dr Temple.

This award acknowledges the important impact this device could have in preventing sight loss worldwide. In the UK alone, AMD affects more than 600,000 people and is estimated to cost the healthcare system £1.6 billion annually.

The University of Bristol's Pro Vice-Chancellor for Research, Professor Nishan Canagarajah, said:

"It's very exciting to see University of Bristol research into something as niche as how octopuses view the world, lead to a screening tool for the biggest cause of sight loss among humans worldwide. The University is very proud of its achievements in research impact and it is fantastic that Dr Temple's achievements have been recognized with such a prestigious award."

Dr. Karen Lewis, interim Executive Director, Innovation and Skills, BBSRC, said:

"The BBSRC Innovator of the Year competition recognizes and rewards BBSRC-funded scientists that have identified and taken an active part in realizing the impact from their research. Dr. Temple's technology has the potential to make a significant difference to people's lives, the journey that Dr. Temple is taking to realize this opportunity from very fundamental research epitomizes the spirit of the competition. This was recognized by the Panel in awarding the BBSRC Innovator of the Year to Dr. Temple."

As well as being named Innovator of the Year 2017, Dr Temple also received the award in the Commercial Impact category.

In 2016, Dr. Temple received £500,000 in funding from Innovate UK, which launched Azul Optics Ltd, the Bristol-based start-up that is commercializing the device. Azul Optics has since secured an additional £310,000 in private investment.