This article perpetuates the misconception that the cause of fibromyalgia is primarily in the brain:
"Clauw explained that fibromyalgia pain comes more from the brain and spinal cord than from areas of the body in which someone may experience peripheral pain. The condition is believed to be associated with disturbances in how the brain processes pain and other sensory information. He said physicians should suspect fibromyalgia in patients with multifocal (mostly musculoskeletal) pain that is not fully explained by injury or inflammation."

This research study demonstrates the origin is physiological, and found in nerve tissue structures in the body.

http://www.ncbi.nlm.nih.gov/pubmed/23691965/

RESULTS:
AVS had significantly increased innervation among FM patients. The excessive innervation consisted of a greater proportion of vasodilatory sensory fibers, compared with vasoconstrictive sympathetic fibers. In contrast, sensory and sympathetic innervation to arterioles remained normal. Importantly, the sensory fibers express α2C receptors, indicating that the sympathetic innervation exerts an inhibitory modulation of sensory activity.
CONCLUSIONS:
The excessive sensory innervation to the glabrous skin AVS is a likely source of severe pain and tenderness in the hands of FM patients. Importantly, glabrous AVS regulate blood flow to the skin in humans for thermoregulation and to other tissues such as skeletal muscle during periods of increased metabolic demand. Therefore, blood flow dysregulation as a result of excessive innervation to AVS would likely contribute to the widespread deep pain and fatigue of FM. SNRI compounds may provide partial therapeutic benefit by enhancing the impact of sympathetically mediated inhibitory modulation of the excess sensory innervation.

SNRI compounds may provide relief for this specific aspect of FMS/CPS, but do not address the loss of elasticity in myelin, inflammation and several other serious symptoms. There is also the risks of adverse side effects.

Whole plant cannabis extract oil with the proper content & ratio of cannabinoids, other terpenoids, terpenes and flavonoids addresses all the symptoms of FMS/CPS without risk of serious adverse side effects. US DHHS has held patent #6630507, Cannabinoids as Antioxidants and Neuroprotectants, for over a decade and NIH-OTT licensed that patent several years ago - but only for manufacture of "dietary & nutritional supplements", rather than actual therapeutic medicine. Despite these facts, and the fact GW Pharmaceuticals currently has two plant sourced cannabinoid based, patented compounds undergoing FDA testing (Sativex & Epidiolex), cannabis remains listed as a Schedule 1 Controlled Substance. Cannabis is easily cultivated, and carries no risk of fatal overdose associated with many prescription pharmaceutical compounds. In the words of DEA Administrative Law Judge Francis Young, in his 1988 ruling against the DEA during the internal petition process: "Marijuana, in its natural form, is one of the safest therapeutically active substances known to man.  By any measure of rational analysis marijuana can be safely used within a supervised routine of medical care."

Cannabis prohibition is unscientific, irrational, unconstitutional and based entirely on lies and propaganda intended to protect the profits of vested interests - not public health and safety. One does not need to smoke cannabis to derive therapeutic benefits. Juicing raw plants is extremely beneficial and advocated by Dr. William Courtney, who witnessed an 8 month old patient diagnosed with an inoperable glioblastoma multiforme (brain tumor) recover completely within a year with no treatment regimen other than whole plant cannabis extract oil. Effects were apparent within 2 months of the start of treatment.

Cannabis cures.