Yes, the outcomes of changes in DNA methylation due to cannabis use could potentially be either beneficial or negative. DNA methylation is a complex process that plays a crucial role in gene regulation and expression. Changes in methylation patterns can have diverse effects on health, depending on various factors, including which genes are affected and the context of these changes.

1. **Potential Negative Outcomes:** Altered DNA methylation patterns have been associated with various health issues, including an increased risk of certain diseases. For example, abnormal methylation in certain genes could potentially contribute to the development of cancers or impact immune function.

2. **Potential Beneficial Outcomes:** On the other hand, some changes in DNA methylation might have protective or therapeutic effects. For instance, methylation changes could potentially downregulate harmful genes or be involved in adaptive responses to environmental factors.

It's important to recognize that the relationship between cannabis use, DNA methylation, and health outcomes is still not fully understood. The specific outcomes of DNA methylation changes due to cannabis use would depend on a variety of factors, including the individual's genetic background, overall health, and environmental interactions. More research is needed to elucidate these relationships and to understand the broader implications of cannabis use on human health.