I've was born and lived in the US all my life. I've traveled the world in my work and find that this is by far the best place to live. Contraindication is:  When it comes to malpractice in the medical arena, the US has a strong propensity to place $$$ above cures and remedies for all forms of desease.  Greed is definately profound in my beloved country.  I have had symptoms of PD for 5 years and it is getting worse by the year.  ISRADIPINE is a drug which has been used for 10 years or so for hypertension.  It has been shown to reduce symptoms of PD in mice. The Isradipine CR has been shown to have a neuroprotective effect in preclinical models of parkinsonism (see reference: Simuni T, Martel A, Zadikoff C, Videnovic A, Vainio L, Weaver F, Williams K, Surmeier DJ.  Safety and tolerability of isradipine, a dihydropyridine calcium channel blocker, in patients with early Parkinson’s disease
The research is being conducted at Northwestern University.
While these studies are beneficial, they leave thousands of us to shake on and die.  I have high blood pressure and I am going to switch to Isradipine asap. Write/call your gov. reps and tell them what you feel about all this red tape involving the FDA.  Ask them if they have a relative or friend with PD. You see, we have lost approx. 50% of our dopamine producing cells back before our symptoms surfaced so we are playing catch up at best.
Please feel free to copy my post and send with your comments to your reps and the FDA.  May God bless us as we rely on our slow medical research system to function.