You state"molnupiravir treatment does not seem to cause a consistent accumulation of mutations at any specific sites across the viral genome. This nullifies the possibility of molnupiravir-induced viral adaptation."

It is not clear to me as to why a mutation in even one virus particle that gives it survival advatage will not cause that particular virus to grow more. In other words, you do not need site specific mutagenesis, only survival advantage of a mutation.