People treating their autistic children biomedically already know this: it's one of the principle theories behind treatment. How is this unrelated to the MMR? Without proper methylation the body can't cope with poisons and toxins--like the MMR and the dtap. Supplements already exist to counteract poor methylation, so why would you need to find a 'medication' to do the same job? I guess it's because some doctors have the 'cranky notion' that getting kickbacks from vaccine manufacturers is ethical medicine.