That is intriguing, but nevertheless cannot allow for drawing conclusions. One reason is already mentioned; those two groups did not differ on memory score tests. While though it is pointed out that in Alzheimer’s memory changes lag behind MRI changes, it does not necessarily apply here. In Alzheimer’s the prospects are downhill for yet-unveiled pathology reasons. In perimenopause however, which is different from a fully established menopause, prospects are presumably better if the body's adaptation to hormonal deficit is allowed-when paraovarian estrogen synthesis( and unknown other physiologic compensation) occurs! This is actually one basic reason why such comparison studies should be made not at the early peri-menopause period, but much longer because in most women final postmenopause takes a decade to be fully established.
Maria Jasmine Freeman