"The study analysis showed that S-IgG levels best predicted the neutralization activity against BQ.1.1. Yet, 59.6% of the individuals with detectable S-IgG levels over 1000 binding antibody units (BAU)/ml showed no significant neutralizing activity against BQ.1.1. It highlighted that low S-IgG levels were inadequate for accurate assessment of the neutralization activity against BQ.1.1." Layperson here but this sounds like the method to measure vaccine effectiveness by measuring increased levels in the blood doesn't translate to actual immunity against the virus. This has been a criticism of how Covid jabs "effectiveness" has been lacking but in a lab it appears to provide a boost that doesn't translate to actual immunity and real world data seems to show any benefits turn negative over time and it doesn't seem like it is understood why. Boosting for high antibody levels while not preventing infection seems like a sure way to create variants that can evade the leaky jabs.