This is not surprising. Although there are many who continue to say that estrogen benefits the brain, this new study is in line with other studies that say otherwise. HRT raises the risk of dementia and shrinks certain parts of the brain responsible for thinking and memory. Older women who are obese, which correlates with high blood levels of estradiol, are alo at increased risk for dementia and memory problems. Interestingly, menopause (loss of estrogen) was recently shown NOT to negatively affect women's memory and treatment for breast cancer with aromatase inhibitors (which causes a 95-98% depletion of estrogen) does not adversely affect cognition.

I'm glad to see yet more evidence that supports the notion that estrogen, either your own or the kind you take as a pharmaceutical, is not this magical substance that shields women from anything that ails them.