We are sorry to hear that GEM was not effective for your wife, Josh.  Unfortunately, every women's body reacts differently to any type of over the counter or prescribed medication.  The use of natural products often requires more time to have an effect than most pharmaceuticals.  We have thousands of women across America taking GEM Keep it cool daily and have felt significant relief.  We strongly recommend that women take GEM every day for the full 32 days.  In some cases, where results are slower, we would suggest trying GEM for little longer.  We believe in our product and back it with a 100% 32 day money back guarantee.  We would love to have a conversation with your wife to see where improvements can be made in our customer service area.  If that doesn't work for you, please send your order information to [email protected] and we will be happy to assist you in getting a full refund.