Why did Pfizer and Moderna focus on the spike protein?

Opinion

... in response to The emergence and spread of the SARS-CoV-2 Lambda (B.1.621) variant

Why did Pfizer and Moderna focus on the spike protein?

Paul Wolf says:

August 23, 2021 at 4:42 PM

I think it was a mistake for the mNRA vaccines to target the spike protein. The fact that it plays an important role in infecting the host cells isn't what's important. Any part of the virus could be targeted, such as the N Terminal Domain, or any other part. This is what how the traditional vaccines work, using deactivated virus. As a result, the spike protein has mutated and is no longer an area that can be targeted by new vaccines.

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- For speed to develop a vaccine and efficacy in stopping it. Mutations
  
  Glenn Van Moffaert says:
  
  August 25, 2021 at 8:15 AM
  
  For speed to develop a vaccine and efficacy in stopping it. Mutations happen all the time.
  
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