Cancer Research UK (CRUK) provides comprehensive information for anyone affected by cancer. 1 in 2 people in the UK will develop cancer in their lifetime. Harpal Kumar, CRUK chief executive, said: Our aim is that one day everyone will beat cancer and the more research we can fund, the sooner that day will come. According to CRUK, there is no single cause for any one type of cancer. Most cancers start due to gene changes that happen over a person’s lifetime. Cancer and its treatments can affect body systems. Some cancers can’t be cured but treatment is often able to control them for some years. Developing countries already have a high burden of cancers. As developing countries take on a more Western lifestyle, cancers that were once rare (breast, lung and colon cancers) are becoming more common. CRUK publishes a twice-monthly professional medical journal, the British Journal of Cancer. Scientists know that there are a number of chemical, physical and biological agents that have been shown to trigger the mistakes in the cell blueprint that cause cancer; cancer can sometimes develop without any specific causes. Scientists know that cancers are classified in two ways: by the type of tissue in which the cancer originates (histological type) and by primary site, or the location in the body where the cancer first developed. From a histological standpoint there are hundreds of different cancers. It is important to understand that cancer originating in one body organ takes its characteristics with it even if it spreads to another part of the body. The Father of Oncology knows that primary tumors always develop at body sites of excessive iron deposits. Such deposits can be inherited or acquired. At the cellular level, cancer occurs when cellular iron overload chaotically affects cellular molecules and organelles (DNA, chromosomes, mitochondria, lysosomes, etc). Cellular iron overload creates chaotic mistakes/errors in DNA, chromosomal abnormalities, chromothripsis and mitotic catastrophes. Cancer encompasses a class of heterogeneous diseases that differ on a cellular and molecular level - even within subtype. Intratumoral injections of iron-deficiency agents (ceramic needles) are needed when tumors cannot be removed with surgery (ceramic blades). Clinical personalized iron-deficiency methods can neutralize metastases and micrometastases. Scientists know only that excess iron can lead to toxicity because this element can catalyze the conversion of hydrogen peroxide into free radicals; iron overload is a risk factor for cancer in general and liver cancer in particular. Cancer is a major cause of mortality and morbidity in the UK in 2015 because scientists and clinicians don’t understand that iron is a cancer creator. Cancer is a single disease with a single cause; cancer is a disease of iron-overloaded cells.