1. dean reinke on tPA therapy improves outcomes for patients suffering acute ischemic stroke
    dean reinke dean reinke United States says:
    May 3, 2014 at 10:22 PM

    What do you do for the 88% of patients that tPA doesn't work on? What is being done to stop the neuronal cascade of death in the first week after tPA blows out the clot? Which one of these five causes are you working on?
    1.  glutamate poisoning
    2.  excitotoxicity
    3.  Capillaries that don't open due to pericytes
    4.  Inflammatory action leaking through the blood brain barrier.
    5.  Lysosomal Membrane Permeabilization as a Key Player in Brain Ischemic Cell Death: a “Lysosomocentric” Hypothesis for Ischemic Brain Damage

    Reply
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