Live-Cell Analysis of Cell Subsets and Heterogeneity

Our new cell-by-cell analysis module allows users to ‘count and classify’ heterogeneity in cell populations over time.

This software uses novel algorithms to segment the HD phase-contrast images which facilitates (1) label-free true cell counting (2) extraction of basic morphological features of individual cells (e.g. size, shape), and (3) measurement of fluorescence intensity that originates from within each cell (‘fluorescence within a phase boundary’). The ability to analyse at a cell-by-cell level will enable the characterisation of subsets and the power to monitor these individual groups in their response to various stimuli.

Presenter

Dr. Clare Szybut, Senior R&D Scientist

Clare is currently a Senior Scientist at Essen BioScience working within the European based research team where she is involved in the research and development of novel kinetic applications for Essen’s IncuCyte™ live-cell analysis system to expand capabilities.

She is a highly experienced cellular biologist with 10 years’ experience.  She gained a PhD in molecular cell biology and has worked in the Biotech industry where she has gained broad technical experience in both biological and biochemical assay design.

In this webinar Clare will discuss:

• Overview and validation of the cell-by-cell analysis module
• How cell-by-cell analysis enables monitoring and quantification of dynamic phenotypic changes in heterogeneous populations
• Examples of how the software may be used for cell subset identification in order to provide an end-to-end solution for the study of heterogeneous populations in 96 well format