nanoComposix (a Fortis Life Sciences Company) is a world-leading manufacturer of nanoparticles.1,2 The company offers an array of point-of-care diagnostic tests, typically referred to as lateral flow tests. These tests leverage the many benefits of colloidal gold to better ensure sensitivity and specificity.
The development and commercialization of lateral flow assay tests continue to present several unique challenges. nanoComposix offers its clients a cost-effective, premium-quality end-to-end solution for sensitive lateral flow tests leveraging colloidal gold.
Customers employing nanoComposix’s colloidal gold for rapid diagnostic tests will benefit from expert support, from feasibility and initial development through to commercialization.
Image Credit: nanoComposix
Using lateral flow
Lateral flow immunoassays, also called immunochromatography strips, are straightforward devices used to detect the absence or presence of a target analyte.
Target analytes range from pathogens to biomarkers, and they can be detected in a variety of different sample types, from food or water to human, animal, and other biological samples.
Two of the most prominent and widely recognized uses of lateral flow tests are those designed to detect the presence of pregnancy hormones or the SARS-CoV-2 protein. However, lateral flow tests are used across a wide range of applications and with a diverse array of sample matrices. These tests are found in markets such as:
- Veterinary diagnostics
- Food safety
- Clinical testing
- Environmental testing
Typical sample matrices include:
- Saliva
- Urine
- Whole blood
- Serum
- Other bodily fluids
- Food
Benefits of lateral flow with colloidal gold
The rapid influx of a wide range of lateral flow tests into the market has led to many products struggling with detection limits and sensitivity.
Leveraging the benefits of colloid gold from nanoComposix allows developers of lateral flow tests to increase their target analyte's specificity, sensitivity, and detection limit.
Scaled production
nanoComposix is one of the largest gold nanoparticle manufacturers in the world. The company’s experience with scaled production allows it to produce the highest-quality and lowest-priced gold colloid, ideally suited for rapid diagnostic tests. No commercial use license is required for the company’s gold colloid products.
Highest quality
All gold nanoparticles are provided with a comprehensive characterization sheet to ensure that each lot precisely meets the required specifications.
The mass concentration and optical density of the gold are measured. This allows users to calculate the binding surface area accurately —a vital consideration when optimizing antibody loading. Large lots and multi-year stability are crucial to minimizing manufacturing risk.
Outstanding support
nanoComposix boasts a proven track record of supporting its customers, and dedicated technical support personnel are on hand to answer any pre-sale or post-sale questions. The company also offers the option of bringing assay development in-house.
References and further reading
- Gold Nanoparticles Market Size, Share, Trends, By Type (Nanorods, Nanoshells, Nanocages, Others), By End-use (Electronics, Healthcare, Chemicals, Others), By Application (Imaging, Sensors, Others), and By Region Forecast to 2030
- https://www.transparencymarketresearch.com/gold-nanoparticles-market.html
About nanoComposix
Since 2004, nanoComposix has provided monodisperse and unagglomerated metal and metal-oxide nanomaterials to thousands of customers. Hundreds of different variants of material, size, shape, and surface are available as stock products and we have produced over 2000 custom core/shell, biofunctionalized, fluorescent, and magnetic nanocomposites to meet client specifications. nanoComposix produced the NIST nanosilver reference material and our particles have been utilized in over 2000 peer-reviewed publications. All of our materials are supplied with certificates of analysis that include electron microscopy, hydrodynamic diameter, and optical data for each batch to guarantee products meet specifications.
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